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Cell line · CVCL_1776

TYK-nu

Cancer cell line, Homo sapiens. High grade ovarian serous adenocarcinoma. 35 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. TYK-nu. Cell lines, record CVCL_1776. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1776

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Cell line

As Cellosaurus gives it.

Name
TYK-nu
Accession
CVCL_1776
RRID
RRID:CVCL_1776
Synonyms
TYK-NU, TYKnu, TYKNU
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
38Y
Category
Cancer cell line
Diseases
High grade ovarian serous adenocarcinoma (NCIt C105555)
Entry created
2012-04-04
Entry updated
2025-11-27

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers35

PaperJournalYearHow we knowRetractedSource
A chemoresistance-associated proliferation gene signature identified by single-cell and machine learning analysis predicts prognosis in high-grade serous ovarian carcinoma.Transl Oncol2026Its Methods give the RRID and name the linePubMed
Preclinical Characterization of CLSP-1025, a First-in-Class, Mutation-Specific T-Cell Engager Targeting a Neoantigen Derived from a Common p53 Mutation.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
Proteomic analysis of malignant ascites and its impact on ovarian cancer spheroids.Clin Proteomics2026Its Methods give the RRID and name the linePubMed
Repurposing of ivacaftor shows potential to treat ROR1 expressing high-grade serous ovarian cancer.Ther Adv Med Oncol2026Its Methods give the RRID and name the linePubMed
PLK1 or WEE1 inhibition targets homologous recombination repair proficiency in BRCA1/2 wild-type high-grade serous ovarian cancer.Cell Death Dis2025Its Methods give the RRID and name the linePubMed
Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors.Clin Cancer Res2025Its Methods give the RRID and name the linePubMed
Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer.Mol Oncol2025Its Methods give the RRID and name the linePubMed
Systematic profiling of cancer-fibroblast interactions reveals drug combinations in ovarian cancer.Mol Oncol2025Its Methods give the RRID and name the linePubMed
Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers.NPJ Precis Oncol2025Its Methods give the RRID and name the linePubMed
Pan-cancer proteomic map of 949 human cell lines.Cancer Cell2022Cellosaurus cites itPubMed

1 to 10 of 35

See all 35 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itTYK-nu.CP-rCVCL_3221

Source Cell lines

Cell banks1

Cell bankCatalog numberStatus
JCRBJCRB0234.0

Source JCRB

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1776

GET https://conductscience.org/api/cell-lines/v1/CVCL_1776/papers?page=2