Cell line · CVCL_1870
MEC-1
Cancer cell line, Homo sapiens. Chronic lymphocytic leukemia. 33 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. MEC-1. Cell lines, record CVCL_1870. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1870
On this page
Cell line
As Cellosaurus gives it.
- Name
- MEC-1
- Accession
- CVCL_1870
- RRID
- RRID:CVCL_1870
- Synonyms
- MEC1
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 61Y
- Category
- Cancer cell line
- Diseases
- Chronic lymphocytic leukemia (NCIt C3163); B-cell chronic lymphocytic leukemia (ORDO Orphanet_67038)
- Derived from
- Peripheral blood (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers33
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival. | Mol Oncol | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Genetically distinct microenvironment determines cancer survival and response to therapy in mice. | bioRxiv | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Design optimization of antibody-ligand motifs to enhance CAR-T redirection activity against solid tumors. | Cell Rep Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Epigenetic activation of EBV BGLF4 determines antiviral-based regimen response in EBV+CNS lymphoproliferative disease. | Blood Neoplasia | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Evaluation of the Role of AID-Induced Mutagenesis in Resistance to B-Cell Receptor Pathway Inhibitors in Chronic Lymphocytic Leukemia. | Curr Issues Mol Biol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| DUSP11 is an Intracellular Innate Immune Checkpoint in Lung Adenocarcinoma. | Cancer Immunol Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Dynamic stimulation promotes functional tissue-like organization of a 3D human lymphoid microenvironment model in vitro. | Cell Rep Methods | 2025 | Its Methods give the RRID and name the line | PubMed | |
| DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response. | Blood Cancer Discov | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Aberrantly Expressed Mitochondrial Lipid Kinase, AGK, Activates JAK2-Histone H3 Axis and BCR Signal: A Mechanistic Study with Implication in CLL Therapy. | Clin Cancer Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects. | Cancer Res Commun | 2024 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 33
See all 33 papersRelatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| From the same person | MEC-2 | CVCL_1871 |
Source Cell lines
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| DSMZ | ACC-497 |
Source DSMZ
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1870
GET https://conductscience.org/api/cell-lines/v1/CVCL_1870/papers?page=2