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Cell line · CVCL_1906

HEp-2

Cancer cell line, Homo sapiens. Human papillomavirus-related endocervical adenocarcinoma. Cellosaurus records it as contaminated. 50 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HEp-2. Cell lines, record CVCL_1906. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1906

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Cell line

As Cellosaurus gives it.

Name
HEp-2
Accession
CVCL_1906
RRID
RRID:CVCL_1906
Synonyms
Hep-2, HEP-2, Hep2 (HeLa derivative), HEp-2/HeLa, Hep 2, Hep2, HEp2, HEP2, H.Ep.-2, H.Ep. #2, H.Ep. No. 2, Hep II, Human Epidermoid carcinoma #2, Human Epithelioma-2
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
30Y6M
Category
Cancer cell line
Diseases
Human papillomavirus-related endocervical adenocarcinoma (NCIt C27677)
Derived from
Uterus, cervix (in situ)
Parent
HeLa (CVCL_0030)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems1

ProblemCellosaurus's note
Contaminated
Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from a 56 year old male patient with a laryngeal carcinoma.

Source Cellosaurus

Papers50

PaperJournalYearHow we knowRetractedSource
Distinct mechanisms of neutralization by antibodies targeting a conserved pneumovirus F epitope.bioRxiv2026Its Methods give the RRID and name the linePubMed
Punicalin targets RSV glycoprotein and fusion protein at non-overlapping sites to prevent viral escape.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Long-term stability of the GMP-compliant recombinant BCG vaccine against human RSV under quality control analyses.iScience2026Its Methods give the RRID and name the linePubMed
Regulation of antiviral immunity by PD-1 during respiratory syncitial virus infection and upon vaccination.iScience2026Its Methods give the RRID and name the linePubMed
Respiratory Syncytial Virus Nonstructural Protein 1 Inhibits Production of Cytokines and Chemokines by Differentiated Primary Nasal Epithelial Cells Cultured at Air-Liquid Interface.J Innate Immun2026Its Methods give the RRID and name the linePubMed
Viral infection and brain inflammation with seizures in PARK7 deficiency.J Hum Immun2026Its Methods give the RRID and name the linePubMed
Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibody.EBioMedicine2026Its Methods give the RRID and name the linePubMed
Molecular mechanism of resistance to lonafarnib conferred by mutations in the cysteine-rich region of respiratory syncytial virus fusion glycoprotein and discovery of a lonafarnib-derived antiviral PROTAC.
J Virol2026Its Methods give the RRID and name the linePubMed
Respiratory syncytial virus downregulates the airway aryl hydrocarbon receptor pathway: implication for the development of a novel therapeutic target.Am J Physiol Lung Cell Mol Physiol2025Its Methods give the RRID and name the linePubMed
No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.PLoS One2025Its Methods give the RRID and name the linePubMed

1 to 10 of 50

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Relatives10

RelationCell lineAccessionProblemSource
ParentHeLaCVCL_0030Cell lines
Derived from itBanCVCL_WH94Has a recorded problemCell lines
Derived from itDRHEp2CVCL_W888Has a recorded problemCell lines
Derived from itHEp-2 clone 2BCVCL_2817Has a recorded problemCell lines
Derived from itHEp-2-NS1CVCL_A8JPHas a recorded problemCell lines
Derived from itHEp-2/VCRCVCL_B7H7Has a recorded problemCell lines
Derived from itHEp-2CCVCL_2940Has a recorded problemCell lines
Derived from itHEp2-Mx2/EGFP L1D7CVCL_RX04Has a recorded problemCell lines
Derived from itHEp2-Mx2/EGFP L1G5CVCL_RX05Has a recorded problemCell lines
Derived from itHep-2 TPFRCVCL_GZ00Has a recorded problemCell lines

Cell banks13

Cell bankCatalog numberStatusSource
ATCCCCL-23ATCC
AddexBioC0050001/4983Cellosaurus
BCRC60042DiscontinuedCellosaurus
BCRJ0101BCRJ
CCLVCCLV-RIE 0141Cellosaurus
CCTCCGDC0004Cellosaurus
CLS300397CLS
ECACC86030501ECACC
IZSLERBS TCL 23Cellosaurus
KCLB10023KCLB

1 to 10 of 13

See all 13 cell banks

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_1906

GET https://conductscience.org/api/cell-lines/v1/CVCL_1906/papers?page=2

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