Cell line · CVCL_1T15
222
Cancer cell line, Homo sapiens. Ovarian mixed germ cell tumor. Cellosaurus records it as contaminated. 5 papers.
4 sourcescell-lines-2026-11-14-0.1.0
Cite this record
ConductScience Library. 222. Cell lines, record CVCL_1T15. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_1T15
On this page
Cell line
As Cellosaurus gives it.
- Name
- 222
- Accession
- CVCL_1T15
- RRID
- RRID:CVCL_1T15
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 12Y
- Category
- Cancer cell line
- Diseases
- Ovarian mixed germ cell tumor (NCIt C8114); Mixed germ cell tumor (ORDO Orphanet_180234)
- Derived from
- Ascites (metastatic)
- Parent
- PA-1 (CVCL_0479)
- Entry created
- 2015-07-08
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Contaminated | Shown to be a PA-1 derivative (PubMed=22710073). Originally thought to be an ovarian carcinoma. |
Source Cellosaurus
Papers5
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination. | Gynecol Oncol | 2012 | Cellosaurus cites it | PubMed | |
| Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide. | J Natl Cancer Inst | 1998 | Cellosaurus cites it | PubMed | |
| p53 gene mutation analysis and antisense-mediated growth inhibition of human ovarian carcinoma cell lines. | Gynecol Oncol | 1996 | Cellosaurus cites it | PubMed | |
| Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines. | J Immunol | 1991 | Cellosaurus cites it | PubMed | |
| Synergy is documented in vitro with low-dose recombinant tumor necrosis factor, cisplatin, and doxorubicin in ovarian cancer cells. | Gynecol Oncol | 1990 | Cellosaurus cites it | PubMed |
Relatives2
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | PA-1 | CVCL_0479 | Cell lines | |
| Derived from it | 222TR | CVCL_1T16 | Has a recorded problem | Cell lines |
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_1T15
GET https://conductscience.org/api/cell-lines/v1/CVCL_1T15/problems