Cell line · CVCL_2142

NK-92

Cancer cell line, Homo sapiens. Natural killer cell lymphoblastic leukemia/lymphoma. 60 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. NK-92. Cell lines, record CVCL_2142. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_2142

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Cell line

As Cellosaurus gives it.

Name: NK-92
Accession: CVCL_2142
RRID: RRID:CVCL_2142
Synonyms: NK92, Natural Killer-92, NK-92.05, Neukoplast, aNK
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 50Y
Category: Cancer cell line
Diseases: Natural killer cell lymphoblastic leukemia/lymphoma (NCIt C82217)
Derived from: Peripheral blood (in situ)
Cell type: Natural killer cell
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and noncommercial suppliers of NK-92 cells. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support.

Problem

Cellosaurus's note

Caution

This cell line is exclusively owned and controlled by NantKwest, Inc. NantKwest and its affiliate, Brink Biologics, Inc. are the sole authorized distributors for both commercial and non-commercial research requestors. There are no other authorized commercial and noncommercial suppliers of NK-92 cells. Contact NantKwest and Brink Biologics for information concerning current inventory and cell line use and support.

Source Cellosaurus

Papers60

Paper	Journal	Year	How we know	Source
Hypoxic Preconditioning Restores NK Cell Metabolic Fitness by Attenuating MAPK Signaling to Potentiate Antitumor Immunity in Lung Cancer	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
A metabolic-oxidative axis contributes to NK cell cryo-vulnerability.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR-NK Therapeutic Strategies.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
A fully human pan VL9 HLA-E TCRm antibody enables functional dissection of HLA-E biology and checkpoint signaling.	iScience	2026	Its Methods give the RRID and name the line	PubMed
Radiation-induced MYB reduction unleashes TIM-3 expression in NK cells to attenuate antitumor immunity in colorectal cancer.	J Transl Med	2026	Its Methods give the RRID and name the line	PubMed
Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells.	PLoS One	2026	Its Methods give the RRID and name the line	PubMed
The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity.	Cell Commun Signal	2026	Its Methods give the RRID and name the line	PubMed
Orosomucoid 2 promotes colorectal cancer liver metastasis by suppressing natural killer cell-mediated antitumor immunity by remodeling the serine and one-carbon metabolism pathway.	Mol Cancer	2026	Its Methods give the RRID and name the line	PubMed
Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 60

See all 60 papers

Relatives19

Relation	Cell line	Accession	Source
Derived from it	GFP-CD16-F/F.NK-92	CVCL_W733	Cell lines
Derived from it	GFP-CD16-V/V.NK-92	CVCL_W734	Cell lines
Derived from it	HyCyte NK-92 KO-hADORA2A	CVCL_F4IS	Cell lines
Derived from it	HyCyte NK-92 KO-hHMGB2	CVCL_F1SL	Cell lines
Derived from it	HyCyte NK-92 KO-hZYX	CVCL_F1SM	Cell lines
Derived from it	HyCyte NK-92 stable cell line for hCD64 overexpression	CVCL_F4LA	Cell lines
Derived from it	NK-92 GFP	CVCL_VN56	Cell lines
Derived from it	NK-92 clone 1	CVCL_C7GQ	Cell lines
Derived from it	NK-92 clone 2	CVCL_C7GR	Cell lines
Derived from it	NK-92.26.5	CVCL_VN57	Cell lines

1 to 10 of 19

See all 19 relatives

Cell banks6

Cell bank	Catalog number	Status	Source
ATCC	CRL-2407		ATCC
AddexBio	C0003026/NA	Discontinued	Cellosaurus
BCRC	60414	Discontinued	Cellosaurus
CCTCC	GDC0052		Cellosaurus
DSMZ	ACC-488		DSMZ
Hysigen	TCH-C292		Hysigen

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_2142

GET https://conductscience.org/api/cell-lines/v1/CVCL_2142/papers?page=2

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