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Cell line · CVCL_2478

HCT 8

Cancer cell line, Homo sapiens. Colon adenocarcinoma. 43 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HCT 8. Cell lines, record CVCL_2478. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_2478

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Cell line

As Cellosaurus gives it.

Name
HCT 8
Accession
CVCL_2478
RRID
RRID:CVCL_2478
Synonyms
HCT-8, HCT8
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
67Y
Category
Cancer cell line
Diseases
Colon adenocarcinoma (NCIt C4349)
Derived from
Colon (in situ)
Cell type
Epithelial cell of colon
Parent
__Parent_cell_line_of_DLD-1/HCT 8/HCT 15/HRT-18 (CVCL_3449)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers43

PaperJournalYearHow we knowRetractedSource
MZF1 Inhibits TGFβ-1/SMAD Signaling by Transcriptionally Activating SnoN to Augment Tumorigenic Potential in Colon Cancer.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
A Novel tRNA Half mt-5'-tiRNA-Tyr Promotes Colorectal Cancer Proliferation via Inducing HARS2 Succinylation.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Cholesterol Reprograms Oxysterol Metabolism via the LOX1/CH25H/CYP7B1 Signaling Axis to Drive Multidrug Resistance in Colorectal Cancer.Hum Mutat2026Its Methods give the RRID and name the linePubMed
Efficacy of an XPO1 inhibitor in combination with irinotecan in a preclinical colorectal cancer model.Front Oncol2026Its Methods give the RRID and name the linePubMed
DDR1 Promotes Immune Evasion in Colorectal Cancer by Orchestrating IL33-Mediated M2-like Polarization of Tumor-Associated Macrophages.Cancer Immunol Res2026Its Methods give the RRID and name the linePubMed
Subcellular Redistribution of Endomembrane GPR15 Promotes NAD+-Mediated Metabolic Reprogramming and Boosts 5-FU Chemosensitivity in Colorectal Cancer.Cancer Res2026Its Methods give the RRID and name the linePubMed
Colorectal cancer-derived osteopontin rewires macrophages into a pro-metastatic M2 state via the PI3K/AKT/CSF1-CSF1R axis.Cell Death Discov2026Its Methods give the RRID and name the linePubMed
Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy.Oncol Res2026Its Methods give the RRID and name the linePubMed
Cathepsin-D-mediated MHC class I degradation contributes to immune evasion in colorectal cancer.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Colorectal cancer cell-derived exosomes induce metabolic reprogramming of cancer-associated fibroblasts to promote colorectal cancer growth.Discov Oncol2025Its Methods give the RRID and name the linePubMed

1 to 10 of 43

See all 43 papers

Relatives10

RelationCell lineAccessionProblemSource
Parent__Parent_cell_line_of_DLD-1/HCT 8/HCT 15/HRT-18CVCL_3449Cell lines
Derived from itHCT-8-Luc2-tdTCVCL_A9CQCell lines
Derived from itHCT-8-mCherryCVCL_A9CRCell lines
Derived from itHCT-8-tdTCVCL_A9CSCell lines
Derived from itHCT-8/E11CVCL_5679Cell lines
Derived from itHCT-8/R1CVCL_5945Cell lines
Derived from itHCT-8/S10CVCL_5947Cell lines
Derived from itHCT-8/S11CVCL_5682Cell lines
Derived from itHCT-8/VCRCVCL_A9CFCell lines
Derived from itHCT-8RCVCL_S851Cell lines

Cell banks9

Cell bankCatalog numberStatusSource
AddexBioC0009017/4907Cellosaurus
BCRC60303BCRC
CCTCCGDC0201Cellosaurus
CLS300210CLS
ECACC90032006ECACC
ICLCHTL99005ICLC
IZSLERBS TCL 97Cellosaurus
KCBKCB 2011103YJCellosaurus
KCLB10244KCLB

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_2478

GET https://conductscience.org/api/cell-lines/v1/CVCL_2478/papers?page=2

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