Cell line · CVCL_2546
KHOS/NP
Cancer cell line, Homo sapiens. Osteosarcoma. 9 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. KHOS/NP. Cell lines, record CVCL_2546. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_2546
On this page
Cell line
As Cellosaurus gives it.
- Name
- KHOS/NP
- Accession
- CVCL_2546
- RRID
- RRID:CVCL_2546
- Synonyms
- KHOS-NP, KHOS NP, KHOSNP, R-970-5, KHOS
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 13Y
- Category
- Cancer cell line
- Diseases
- Osteosarcoma (NCIt C9145); Osteosarcoma (ORDO Orphanet_668)
- Derived from
- Bone, right femur (in situ)
- Parent
- MNNG/HOS Cl #5 (CVCL_0439)
- Entry created
- 2012-04-04
- Entry updated
- 2025-11-27
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers9
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| An inertial-based spiral device for separating rare tumor cells from liquid biopsies. | Bioeng Transl Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Neutrophil elastase promotes low molecular weight cyclin E1 formation to accelerate osteosarcoma proliferation. | Front Immunol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Tocilizumab (monoclonal anti-IL-6R antibody) reverses anlotinib resistance in osteosarcoma. | Front Oncol | 2023 | Its Methods give the RRID and name the line | PubMed | |
| Targeting Podoplanin for the Treatment of Osteosarcoma. | Clin Cancer Res | 2022 | Its Methods give the RRID and name the line | PubMed | |
| Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. | Cancer Cell | 2017 | Cellosaurus cites it | PubMed | |
| Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression. | Mol Cancer Ther | 2015 | Cellosaurus cites it | PubMed | |
| A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. | Cancer Res | 2010 | Cellosaurus cites it | PubMed | |
| p53 functions as a cell cycle control protein in osteosarcomas. | Mol Cell Biol | 1990 | Cellosaurus cites it | PubMed | |
| Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line. | Oncogene | 1988 | Cellosaurus cites it | PubMed |
Relatives4
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | MNNG/HOS Cl #5 | CVCL_0439 | Cell lines | |
| Derived from it | KH OS R1 | CVCL_T431 | Cell lines | |
| Derived from it | KHOS-240S | CVCL_2544 | Cell lines | |
| Derived from it | KHOS-312H | CVCL_2545 | Cell lines |
Cell banks5
| Cell bank | Catalog number | Status | Source |
|---|---|---|---|
| ATCC | CRL-1544 | ATCC | |
| ATCC | CRL-7723 | Discontinued | Cellosaurus |
| CLS | 300235 | CLS | |
| ECACC | 84102903 | ECACC | |
| IZSLER | BS TCL 80 | Cellosaurus |
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_2546
GET https://conductscience.org/api/cell-lines/v1/CVCL_2546/problems