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Cell line · CVCL_2686

PEO1

Cancer cell line, Homo sapiens. BRCA2 syndrome. 58 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. PEO1. Cell lines, record CVCL_2686. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_2686

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Cell line

As Cellosaurus gives it.

Name
PEO1
Accession
CVCL_2686
RRID
RRID:CVCL_2686
Synonyms
PE01, PEO-1, PEO
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
BRCA2 syndrome (NCIt C36101); Ovarian cystadenocarcinoma (NCIt C5228); Hereditary breast and ovarian cancer syndrome (ORDO Orphanet_145)
Derived from
Ascites (metastatic)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers58

PaperJournalYearHow we knowRetractedSource
Targeting oxidative phosphorylation with lixumistat overcomes PARP inhibitor resistance in ovarian cancer.Cell Death Dis2026Its Methods give the RRID and name the linePubMed
Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer.Mol Oncol2026Its Methods give the RRID and name the linePubMed
Targeting p300 Reverses Acidic Microenvironment-Induced PARP Inhibitor Resistance.Cancer Res2026Its Methods give the RRID and name the linePubMed
The Pharmacologic Profile of ART6043, a First-in-Class Clinical DNA Polymerase Theta Polymerase Domain Inhibitor Potentiating PARP Inhibitor Efficacy.Clin Cancer Res2026Its Methods give the RRID and name the linePubMed
DNA Methyltransferase Inhibition Prevents Platinum-Induced Ovarian Cancer Stem Cell Enrichment.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer.Br J Cancer2026Its Methods give the RRID and name the linePubMed
DHX9 Inhibition Enhances Paclitaxel Sensitivity by Inducing Mitotic Failure in Ovarian and Endometrial Cancers.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
Tumor-Infiltrating Nociceptor Neurons in Ovarian Cancer Treatment Resistance.Adv Biol (Weinh)2026Its Methods give the RRID and name the linePubMed
Chromobox 2 Inhibition: A Novel Activity of Alisertib, an Aurora A Kinase Inhibitor.Mol Cancer Ther2026Its Methods give the RRID and name the linePubMed
Metabolic Dependency on De Novo Pyrimidine Synthesis Is a Targetable Vulnerability in Platinum-Resistant Ovarian Cancer.Cancer Res2026Its Methods give the RRID and name the linePubMed

1 to 10 of 58

See all 58 papers

Relatives4

RelationCell lineAccessionProblemSource
Derived from itPEO1-CDDPCVCL_Y032Cell lines
Derived from itPEO1XCVCL_B3UQCell lines
From the same personPEO4CVCL_2690Cell lines
From the same personPEO6CVCL_2691Cell lines

Cell banks3

Cell bankCatalog numberStatusSource
CancerTools151672CancerTools
ECACC10032308DiscontinuedCellosaurus
Ximbio151672Ximbio

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_2686

GET https://conductscience.org/api/cell-lines/v1/CVCL_2686/papers?page=2