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Cell line · CVCL_3517

HPAC

Cancer cell line, Homo sapiens. Pancreatic adenocarcinoma. 71 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HPAC. Cell lines, record CVCL_3517. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_3517

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Cell line

As Cellosaurus gives it.

Name
HPAC
Accession
CVCL_3517
RRID
RRID:CVCL_3517
Synonyms
Hpac
Species
Homo sapiens (Human)
Sex
Female
Age at sampling
64Y
Category
Cancer cell line
Diseases
Pancreatic adenocarcinoma (NCIt C8294)
Derived from
Pancreas (in situ)
Cell type
Pancreatic ductal cell
Entry created
2012-04-04
Entry updated
2026-03-31

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers71

PaperJournalYearHow we knowRetractedSource
Allele-Specific Mechanisms Guide Salvage Therapy to Overcome Daraxonrasib Resistance in Pancreatic Cancer.Cancer Res2026Its Methods give the RRID and name the linePubMed
STING agonist profiling by nucleotide library defines structural determinants of cyclic dinucleotide recognition.iScience2026Its Methods give the RRID and name the linePubMed
Targeting PRMT5 Inhibitor-Induced Adaptation in Pancreatic Cancer with the RBM39 Degrader Indisulam.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
A stress-adaptive lipid kinase axis defines metabolic vulnerabilities in neuroendocrine prostate cancer.Cancer Cell2026Its Methods give the RRID and name the linePubMed
A Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
Overcoming Daraxonrasib Resistance: Allele-Specific Mechanisms Guide Salvage Therapy in Pancreatic Cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed
Acquisition of Resistance to RAS Inhibition Is Associated with the Upregulation of Macropinocytosis through Both PI3K-Dependent and -Independent Signaling.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
The Protein Phosphatase Inhibitor LB100 Targets the Mesenchymal Lineage of Pancreatic Ductal Adenocarcinoma.MedComm (2020)2026Its Methods give the RRID and name the linePubMed
ALDH1A3 promotes the lung metastatic organotropism of pancreatic ductal adenocarcinoma through semaphorin signaling.iScience2026Its Methods give the RRID and name the linePubMed
Characterization and therapeutic suppression of KEAP1-NRF2-driven resistance to KRAS inhibitors in pancreatic and lung cancer.bioRxiv2026Its Methods give the RRID and name the linePubMed

1 to 10 of 71

See all 71 papers

Relatives1

RelationCell lineAccessionProblem
Derived from itKCI-MOH1CVCL_2090Has a recorded problem

Source Cell lines

Cell banks3

Cell bankCatalog numberStatusSource
ATCCCRL-2119ATCC
BCRC60495BCRC
CLS305309CLS

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_3517

GET https://conductscience.org/api/cell-lines/v1/CVCL_3517/papers?page=2