Cell line · CVCL_4358

LL/2 (LLC1)

Cancer cell line, Mus musculus. Malignant tumors of the mouse pulmonary system. 135 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. LL/2 (LLC1). Cell lines, record CVCL_4358. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_4358

On this page

Cell line

As Cellosaurus gives it.

Name: LL/2 (LLC1)
Accession: CVCL_4358
RRID: RRID:CVCL_4358
Synonyms: LL/2 (LLc1), LL/2(LLc1), LL/2, LL2, LLC1, LLC, Lewis lung carcinoma line 1, Lewis lung carcinoma, Lewis Lung Cancer, Lewis-Lung, Lewis Lung
Species: Mus musculus (Mouse)
Category: Cancer cell line
Diseases: Malignant tumors of the mouse pulmonary system (NCIt C21769)
Derived from: Lung (in situ)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	Could be identical to 3LL (Cellosaurus=CVCL_5653).

Source Cellosaurus

Papers135

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
PubMed 42999416	Transl Lung Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
Integrated Computational Pipeline Combining Metabolomics and Network Pharmacology for Bioactive Scaffold Discovery: Application to Antarctic Moss Chorisodontium aciphyllum.	Chem Biodivers	2026	Its Methods give the RRID and name the line	PubMed
Blocking aryl hydrocarbon receptor remodels myeloid-T cell crosstalk and enhances anti-PD-1 response in the tumor microenvironment.	Exp Hematol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Combined HER2-targeted mRNA-LNP vaccine and radiotherapy suppress Lewis lung carcinoma growth in mice: Efficacy and mechanistic insights.	Bioeng Transl Med	2026	Its Methods give the RRID and name the line	PubMed
A Multi-Targeting Chimeric Antigen Receptor-T Cell Platform to Overcome Antigen Heterogeneity in the Treatment of Non-Small Cell Lung Cancer.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis.	Mol Oncol	2026	Its Methods give the RRID and name the line	PubMed
Intravenously deliverable oncolytic virus VET3-TGI favorably alters the tumor microenvironment.	J Immunother Cancer	2026	Its Methods give the RRID and name the line	PubMed
Collagen-Binding IL-15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self-Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
HIF1A+CSF3R+ neutrophils-dominated hypoxic niche induced metabolic reprogramming for neoadjuvant therapy resistance in NSCLC.	J Immunother Cancer	2026	Its Methods give the RRID and name the line	PubMed
TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment.	J Exp Med	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 135

See all 135 papers

Relatives47

Relation	Cell line	Accession	Source
Derived from it	EDITGENE Kras (p.G12C) Point Mutation in LLC Cell Line	CVCL_F5YJ	Cell lines
Derived from it	EDITGENE Kras, p.G12C & Trp53, p.R172H Point Mutation in LLC Cell Line	CVCL_F5YK	Cell lines
Derived from it	EDITGENE LLC-CopGFP	CVCL_F6C8	Cell lines
Derived from it	EDITGENE LLC-FLUC	CVCL_F5UR	Cell lines
Derived from it	EDITGENE Trp53 (p.R172H) Point Mutation in LLC Cell Line	CVCL_F5YL	Cell lines
Derived from it	Genomeditech LLC1 H_SLC39A6	CVCL_E6W9	Cell lines
Derived from it	HyCyte LL/2 (LLC1) KO-mArg2	CVCL_F1R8	Cell lines
Derived from it	HyCyte LL/2 (LLC1) KO-mChchd10	CVCL_F4JI	Cell lines
Derived from it	HyCyte LL/2 (LLC1) KO-mIrf7	CVCL_E1LR	Cell lines
Derived from it	HyCyte LL/2 (LLC1) KO-mItgal	CVCL_F1R9	Cell lines

1 to 10 of 47

See all 47 relatives

Cell banks16

Cell bank	Catalog number	Status	Source
ATCC	CRL-1642		ATCC
AddexBio	C0016030/5000		Cellosaurus
BCRC	60050		BCRC
BCRJ	0145		BCRJ
CLS	305311		CLS
CLS	400263	Discontinued	Cellosaurus
ECACC	90020104		ECACC
EDITGENE	EDC00260		EDITGENE
Hysigen	TCM-C742		Hysigen
IZSLER	BS TCL 216		Cellosaurus

1 to 10 of 16

See all 16 cell banks

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_4358

GET https://conductscience.org/api/cell-lines/v1/CVCL_4358/papers?page=2

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