Cell line · CVCL_4972

MHCC97-H

Cancer cell line, Homo sapiens. Adult hepatocellular carcinoma. 54 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. MHCC97-H. Cell lines, record CVCL_4972. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_4972

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Cell line

As Cellosaurus gives it.

Name: MHCC97-H
Accession: CVCL_4972
RRID: RRID:CVCL_4972
Synonyms: MHCC 97-H, MHCC-97H, MHCC97H, MHCC 97-High metastatic
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 39Y
Category: Cancer cell line
Diseases: Adult hepatocellular carcinoma (NCIt C7956); Adult hepatocellular carcinoma (ORDO Orphanet_210159)
Parent: MHCC97 (CVCL_4971)
Entry created: 2012-04-04
Entry updated: 2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers54

3 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

Paper	Journal	Year	How we know	Source
ZC3H15 in human tumors: a pan-cancer exploration of its clinical significance, molecular function, and association with the tumor immune microenvironment.	Front Immunol	2026	Its Methods give the RRID and name the line	PubMed
USP4-Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Integrative Pan-Cancer Characterization of lncRNA UPK1A-AS1 and Its Role in Hypoxia-Associated Sorafenib Resistance in Hepatocellular Carcinoma.	Anal Cell Pathol (Amst)	2026	Its Methods give the RRID and name the line	PubMed
Metabolic Reprogramming of NSUN2-Mediated m5C Modification Promotes the Progression of Hepatocellular Carcinoma by Restricting Natural Killer Cell-Mediated Cytotoxicity.	Cancer Commun (Lond)	2026	Its Methods give the RRID and name the line	PubMed
A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms.	iScience	2026	Its Methods give the RRID and name the line	PubMed
FKBP52 dictates the dual role of p53 in hepatocellular carcinoma: Mutation-specific prognostic stratification and therapeutic implications.	J Biol Chem	2026	Its Methods give the RRID and name the line	PubMed
Mechanosensors Collaborate to Regulate DNA Damage Repair in Hepatocellular Carcinoma.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed
Targeting Cuproptosis and Ferroptosis via a ROS-Responsive Nanoplatform for Enhanced Synergistic Therapy Against Hepatocellular Carcinoma.	Antioxidants (Basel)	2026	Its Methods give the RRID and name the line	PubMed
The miR-4512/PDZK1IP1 axis in hepatocellular carcinoma: clinical significance, diagnostic value, and functional validation.	BMC Med Genomics	2026	Its Methods give the RRID and name the line	PubMed
Master Regulator SMC1A, Stabilized by N6-Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer-Promoter Interaction of Nestin.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 54

See all 54 papers

Relatives9

Relation	Cell line	Accession	Source
Parent	MHCC97	CVCL_4971	Cell lines
Derived from it	HCCLM3	CVCL_6832	Cell lines
Derived from it	HyCyte MHCC97-H KO-hKLF4	CVCL_F4IG	Cell lines
Derived from it	HyCyte MHCC97-H stable cell line for hPLAUR overexpression	CVCL_F4Q5	Cell lines
Derived from it	HyCyte MHCC97-H-Luc	CVCL_E3I0	Cell lines
Derived from it	MHCC97-H CD44s shRNA	CVCL_VU23	Cell lines
Derived from it	MHCC97-H Scrm shRNA	CVCL_VU24	Cell lines
Derived from it	MHCC97-H c-Met shRNA	CVCL_VU22	Cell lines
Derived from it	MHCC97H-GFP-LC3	CVCL_A9LY	Cell lines

Cell banks1

Cell bank	Catalog number	Status
EDITGENE	EDC00424

Source EDITGENE

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

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NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

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CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_4972

GET https://conductscience.org/api/cell-lines/v1/CVCL_4972/papers?page=2

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