Cell line · CVCL_4973
MHCC97-L
Cancer cell line, Homo sapiens. Adult hepatocellular carcinoma. 18 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. MHCC97-L. Cell lines, record CVCL_4973. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_4973
On this page
Cell line
As Cellosaurus gives it.
- Name
- MHCC97-L
- Accession
- CVCL_4973
- RRID
- RRID:CVCL_4973
- Synonyms
- MHCC 97-L, MHCC97L, MHCC 97-Low metastatic
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 39Y
- Category
- Cancer cell line
- Diseases
- Adult hepatocellular carcinoma (NCIt C7956); Adult hepatocellular carcinoma (ORDO Orphanet_210159)
- Parent
- MHCC97 (CVCL_4971)
- Entry created
- 2012-04-04
- Entry updated
- 2025-11-27
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers18
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis. | Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Impaired nitrogenous waste clearance promotes hepatocellular carcinoma. | Sci Adv | 2026 | Its Methods give the RRID and name the line | PubMed | |
| CRISPR screening reveals that RNA helicase DDX41 triggers ribosome biogenesis and cancer progression through R-loop-mediated RPL/RPS transcription. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| VPS45 Contributes to the Progression of Hepatocellular Carcinoma by Triggering the Wnt/β-Catenin Signaling Pathway. | Mol Carcinog | 2025 | Its Methods give the RRID and name the line | PubMed | |
| HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. | Cancer Res | 2025 | Its Methods give the RRID and name the line | PubMed | |
| SIGLEC15, negatively correlated with PD-L1 in HCC, could induce CD8+ T cell apoptosis to promote immune evasion. | Oncoimmunology | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation. | Cell Rep Med | 2024 | Its Methods give the RRID and name the line | PubMed | |
| CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway. | J Transl Med | 2023 | Its Methods give the RRID and name the line | PubMed | |
| Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines. | iScience | 2022 | Its Methods give the RRID and name the line | PubMed | |
| GNA14's interaction with RACK1 inhibits hepatocellular carcinoma progression through reducing MAPK/JNK and PI3K/AKT signaling pathway. | Carcinogenesis | 2021 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 18
See all 18 papersRelatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| Parent | MHCC97 | CVCL_4971 |
Source Cell lines
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_4973
GET https://conductscience.org/api/cell-lines/v1/CVCL_4973/problems