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Cell line · CVCL_5239

1205Lu

Cancer cell line, Homo sapiens. Cutaneous melanoma. Cellosaurus records it as partially contaminated. 21 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. 1205Lu. Cell lines, record CVCL_5239. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_5239

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Cell line

As Cellosaurus gives it.

Name
1205Lu
Accession
CVCL_5239
RRID
RRID:CVCL_5239
Synonyms
1205-Lu, 1205 Lu, WM 1205LU, WM-1205LU, WM1205Lu, WM1205, LU1205, Lu1205, WC00058
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
37Y
Category
Cancer cell line
Diseases
Cutaneous melanoma (NCIt C3510)
Derived from
Skin (in situ)
Parent
WM793 (CVCL_8787)
Entry created
2012-04-04
Entry updated
2025-08-14

Source Cellosaurus

Problems2

ProblemCellosaurus's note
Partially contaminated
The stock formerly distributed by Coriell (WC00058) contains a significant amount of mouse DNA (DOI=10.4172/1948-5956.1000196). This is not the case of the original Wistar stock which was distributed by Rockland (DOI=10.4172/1948-5956.1000401).
Caution
The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in Cellosaurus and May 2018. The major changes were: Amelogenin: X,Y->X, D16S539: 11,12->10,12, D7S820: 10,12->10, D8S1179: 11,12,14->12,14 and vWA: 16,17->17.

Papers21

PaperJournalYearHow we knowRetractedSource
Extracellular matrix stiffness determines the phenotypic behavior of dedifferentiated melanoma cells through a DDR1/2-dependent YAP mechanotransduction pathway.Oncogenesis2026Its Methods give the RRID and name the linePubMed
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity.Mol Oncol2026Its Methods give the RRID and name the linePubMed
FRA1 drives melanoma metastasis through an actionable transcriptional network.Oncogene2025Its Methods give the RRID and name the linePubMed
The IFNγ-CIITA-MHC II axis modulates melanoma cell susceptibility to NK-cell-mediated cytotoxicity.Mol Oncol2025Its Methods give the RRID and name the linePubMed
FRA1 drives melanoma metastasis through an actionable transcriptional network.bioRxiv2025Its Methods give the RRID and name the linePubMed
PHGDH Induction by MAPK Is Essential for Melanoma Formation and Creates an Actionable Metabolic Vulnerability.Cancer Res2025Its Methods give the RRID and name the linePubMed
Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy.Cell2024Its Methods give the RRID and name the linePubMed
p300 KAT Regulates SOX10 Stability and Function in Human Melanoma.Cancer Res Commun2024Its Methods give the RRID and name the linePubMed
HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.NAR Cancer2024Its Methods give the RRID and name the linePubMed
PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis.Cancer Res2024Its Methods give the RRID and name the linePubMed

1 to 10 of 21

See all 21 papers

Relatives1

RelationCell lineAccessionProblem
ParentWM793CVCL_8787

Source Cell lines

Cell banks3

Cell bankCatalog numberStatus
ATCCCRL-2812Discontinued
CoriellWC00058Discontinued
Rockland51603Discontinued

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_5239

GET https://conductscience.org/api/cell-lines/v1/CVCL_5239/papers?page=2