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Cell line · CVCL_5735

D-54MG

Cancer cell line, Homo sapiens. Glioblastoma. Cellosaurus records it as contaminated. 13 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. D-54MG. Cell lines, record CVCL_5735. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_5735

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Cell line

As Cellosaurus gives it.

Name
D-54MG
Accession
CVCL_5735
RRID
RRID:CVCL_5735
Synonyms
D-54 MG, D54-MG, D54MG, D54Mg, D54, H54
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
53Y
Category
Cancer cell line
Diseases
Glioblastoma (NCIt C3058); Glioblastoma (ORDO Orphanet_360)
Derived from
Brain (in situ)
Parent
A-172 (CVCL_0131)
Secondary accessions
CVCL_7185
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems1

ProblemCellosaurus's note
ContaminatedShown to be a A-172 derivative (ICLAC; personal communication of Bigner, Darell Doty). Originally thought to originate from a 39 year old female patient with a glioblastoma.

Papers13

PaperJournalYearHow we knowRetractedSource
MAGMAS Inhibition Enhances Temozolomide Efficacy in Chemotherapy-Resistant Glioblastoma Models.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature.Cell Rep Med2026Its Methods give the RRID and name the linePubMed
Glioma chemotherapeutic resistance is tied to membrane electrophysiological properties and glycosylation.Bioeng Transl Med2026Its Methods give the RRID and name the linePubMed
STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability.Cancer Res2019Its Methods give the RRID and name the linePubMed
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.Cancer Cell2018Its Methods give the RRID and name the linePubMed
Overexpression of protein kinase C epsilon in astroglial brain tumor derived cell lines and primary tumor samples.Int J Oncol1999Cellosaurus cites itPubMed
Brain tumors.1999Cellosaurus cites itDOI
Functional expression of bombesin receptor in most adult and pediatric human glioblastoma cell lines; role in mitogenesis and in stimulating the mitogen-activated protein kinase pathway.Mol Cell Endocrinol1997Cellosaurus cites itPubMed
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers.Nat Genet1997Cellosaurus cites itPubMed
Human glioma cell lines.1994Cellosaurus cites itDOI

1 to 10 of 13

See all 13 papers

Relatives2

RelationCell lineAccessionProblemSource
ParentA-172CVCL_0131Cell lines
Derived from itD54MG fat-1CVCL_E6ZLCell lines

Cell banks0

None in this release.

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_5735

GET https://conductscience.org/api/cell-lines/v1/CVCL_5735/problems