Cell line · CVCL_6825
CCRF-CEM C7
Cancer cell line, Homo sapiens. Childhood T acute lymphoblastic leukemia. 7 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. CCRF-CEM C7. Cell lines, record CVCL_6825. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_6825
On this page
Cell line
As Cellosaurus gives it.
- Name
- CCRF-CEM C7
- Accession
- CVCL_6825
- RRID
- RRID:CVCL_6825
- Synonyms
- CCRF-CEM-C7, CCRF/CEM-C7, CEM-C7, CEM C7, CEMC7, C7, CEM clone 7
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 3Y11M
- Category
- Cancer cell line
- Diseases
- Childhood T acute lymphoblastic leukemia (NCIt C7953); Precursor T-cell acute lymphoblastic leukemia (ORDO Orphanet_99861)
- Derived from
- Peripheral blood (in situ)
- Cell type
- T-cell
- Parent
- CCRF-CEM (CVCL_0207)
- Entry created
- 2012-04-04
- Entry updated
- 2025-11-27
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers7
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| LRH-1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance. | EMBO Rep | 2022 | Its Methods give the RRID and name the line | PubMed | |
| Splice site mutation in the glucocorticoid receptor gene causes resistance to glucocorticoid-induced apoptosis in a human acute leukemic cell line. | Cancer Res | 1995 | Cellosaurus cites it | PubMed | |
| Increased glucocorticoid responsiveness of CD4+ T-cell clonal lines grown in serum-free media. | In Vitro Cell Dev Biol | 1990 | Cellosaurus cites it | PubMed | |
| The karyotype of the glucocorticoid-sensitive, lymphoblastic human T-cell line CCRF-CEM shows a unique deleted and inverted chromosome 9. | Cancer Genet Cytogenet | 1985 | Cellosaurus cites it | PubMed | |
| Glucocorticoid-resistant human acute lymphoblastic leukemic cell line with functional receptor. | Cancer Res | 1983 | Cellosaurus cites it | PubMed | |
| Isolation and characterization of dexamethasone-resistant mutants from human lymphoid cell line CEM-C7. | Mol Cell Biol | 1981 | Cellosaurus cites it | PubMed | |
| Characterization of a glucocorticoid-sensitive human lymphoid cell line. | Cancer Res | 1977 | Cellosaurus cites it | PubMed |
Relatives8
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Parent | CCRF-CEM | CVCL_0207 | Cell lines | |
| Derived from it | CCRF-CEM C7 3R43 | CVCL_F1W6 | Cell lines | |
| Derived from it | CCRF-CEM C7 3R7 | CVCL_F1W7 | Cell lines | |
| Derived from it | CCRF-CEM C7 4R4 | CVCL_F1W8 | Cell lines | |
| Derived from it | CCRF-CEM C7 ICR 27 | CVCL_F1W5 | Cell lines | |
| Derived from it | CCRF-CEM C7-14 | CVCL_B7AA | Cell lines | |
| Derived from it | CCRF-CEM C7A | CVCL_6826 | Cell lines | |
| Derived from it | CCRF-CEM C7H2 | CVCL_EP75 | Cell lines |
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| CLS | 300398 |
Source CLS
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_6825
GET https://conductscience.org/api/cell-lines/v1/CVCL_6825/problems