Cell line · CVCL_7707
UM-SCC-1
Cancer cell line, Homo sapiens. Floor of mouth squamous cell carcinoma. 33 papers.
4 sourcescell-lines-2026-11-14-0.1.0
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Cite this record
ConductScience Library. UM-SCC-1. Cell lines, record CVCL_7707. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_7707
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Cell line
As Cellosaurus gives it.
- Name
- UM-SCC-1
- Accession
- CVCL_7707
- RRID
- RRID:CVCL_7707
- Synonyms
- UMSCC-1, UM-SCC1, UMSCC1, UM-SCC-01, SCC-1, SCC1, University of Michigan-Squamous Cell Carcinoma-1
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 72Y
- Category
- Cancer cell line
- Diseases
- Floor of mouth squamous cell carcinoma (NCIt C4041); Squamous cell carcinoma of the oral cavity (ORDO Orphanet_502363)
- Derived from
- Oral cavity, floor of mouth (in situ)
- Entry created
- 2012-04-04
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Caution | Indicated as originating from a 60 year old patient in PubMed=3855324 and from a 72 year old in PubMed=1851275 and PubMed=18006756. |
Source Cellosaurus
Papers33
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| SLC15A4 promotes oral cancer progression by regulating TLR9 and activating the JAK/STAT signaling pathway. | Head Face Med | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Genomic Enrichment and Functional Impact of TP53 and CYLD Alterations in Recurrent and Metastatic HPV-Associated Head and Neck Cancer. | Clin Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Targeting PLK1 Reduces MMP10 to Enhance Radiosensitivity in HPV- Head and Neck Cancer. | Clin Cancer Res | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Safety and efficacy of a STAT3-targeted cyclic oligonucleotide: From murine models to a phase 1 clinical trial in pet cats with oral cancer. | Cancer Cell | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Molecular imaging predicts trastuzumab-deruxtecan (T-DXd) response in head and neck cancer xenograft models. | Mol Oncol | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Avelumab induces greater Fc-Fc receptor-dependent natural killer cell activation and dendritic cell crosstalk compared to durvalumab. | Oncoimmunology | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Effects of Vitamin D on tumor cell proliferation and migration, tumor initiation and anti-tumor immune response in head and neck squamous cell carcinomas. | Biomed Pharmacother | 2024 | Its Methods give the RRID and name the line | PubMed | |
| The Role of TGF-β1 and Mutant SMAD4 on Epithelial-Mesenchymal Transition Features in Head and Neck Squamous Cell Carcinoma Cell Lines. | Cancers (Basel) | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Dual anti-HER2/EGFR inhibition synergistically increases therapeutic effects and alters tumor oxygenation in HNSCC. | Sci Rep | 2024 | Its Methods give the RRID and name the line | PubMed | |
| Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p. | Theranostics | 2024 | Its Methods give the RRID and name the line | PubMed |
1 to 10 of 33
See all 33 papersRelatives6
| Relation | Cell line | Accession | Problem | Source |
|---|---|---|---|---|
| Derived from it | 1Cc8 | CVCL_L893 | Cell lines | |
| Derived from it | SCC-1-Cet-R | CVCL_4V02 | Cell lines | |
| Derived from it | SCC-1-Erl-R | CVCL_4V03 | Cell lines | |
| Derived from it | SCC-1-Gef-R | CVCL_4V04 | Cell lines | |
| Derived from it | T409 | CVCL_1Q88 | Has a recorded problem | Cell lines |
| Derived from it | Tu 167 | CVCL_4912 | Has a recorded problem | Cell lines |
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| Millipore | SCC070 |
Source Millipore
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_7707
GET https://conductscience.org/api/cell-lines/v1/CVCL_7707/papers?page=2