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Cell line · CVCL_8561

COS-M6

Transformed cell line, Chlorocebus aethiops. 7 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. COS-M6. Cell lines, record CVCL_8561. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_8561

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Cell line

As Cellosaurus gives it.

Name
COS-M6
Accession
CVCL_8561
RRID
RRID:CVCL_8561
Synonyms
COS-m6, COS M6, COSM6, CosM6, COSm6, COS-1 M6, Cos-1/M6
Species
Chlorocebus aethiops (Green monkey)
Sex
Male
Age at sampling
Adult
Category
Transformed cell line
Derived from
Kidney (in situ)
Parent
COS-1 (CVCL_0223)
Entry created
2012-04-04
Entry updated
2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers7

PaperJournalYearHow we knowRetractedSource
MgATP/MgADP-dependent conformational dynamics and intrinsically disordered regions of vascular KATP channels revealed by cryoEM.bioRxiv2026Its Methods give the RRID and name the linePubMed
AI-based discovery and cryoEM structural elucidation of a KATP channel pharmacochaperone.Elife2025Its Methods give the RRID and name the linePubMed
Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface.Nat Commun2024Its Methods give the RRID and name the linePubMed
ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9.Nat Commun2019Its Methods give the RRID and name the linePubMed
Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM.Elife2019Its Methods give the RRID and name the linePubMed
Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM.Elife2017Its Methods give the RRID and name the linePubMed
Expression of chimeric genes in the early region of SV40.J Mol Appl Genet1983Cellosaurus cites itPubMed

Relatives1

RelationCell lineAccessionProblem
ParentCOS-1CVCL_0223

Source Cell lines

Cell banks0

None in this release.

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_8561

GET https://conductscience.org/api/cell-lines/v1/CVCL_8561/problems