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Cell line · CVCL_9721

66cl-4

Cancer cell line, Mus musculus. Malignant neoplasms of the mouse mammary gland. 13 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. 66cl-4. Cell lines, record CVCL_9721. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_9721

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Cell line

As Cellosaurus gives it.

Name
66cl-4
Accession
CVCL_9721
RRID
RRID:CVCL_9721
Synonyms
66cl4, 66c14, Line 66 clone 4
Species
Mus musculus (Mouse)
Sex
Female
Age at sampling
Age unspecified
Category
Cancer cell line
Diseases
Malignant neoplasms of the mouse mammary gland (NCIt C21678)
Derived from
Mammary gland (in situ)
Parent
66 [Mouse mammary tumor] (CVCL_9722)
Entry created
2012-06-06
Entry updated
2025-11-27

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers13

PaperJournalYearHow we knowRetractedSource
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy.Mol Oncol2026Its Methods give the RRID and name the linePubMed
Metastasis-Associated Wound Repair Promotes Reciprocal Lung Epithelium Activation and Breast Cancer Metastatic Outgrowth.Cancer Res Commun2026Its Methods give the RRID and name the linePubMed
Modulation of fibronectin extracellular matrix enhances anti-tumor efficacy of immune checkpoint blockade.Cell Rep Med2025Its Methods give the RRID and name the linePubMed
EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis.Sci Adv2025Its Methods give the RRID and name the linePubMed
MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer.NPJ Breast Cancer2021Its Methods give the RRID and name the linePubMed
Nephronectin promotes breast cancer brain metastatic colonization via its integrin-binding domains.Sci Rep2020Its Methods give the RRID and name the linePubMed
Novel mouse mammary cell lines for in vivo bioluminescence imaging (BLI) of bone metastasis.Biol Proced Online2012Cellosaurus cites itPubMed
Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix.Mol Cancer Res2005Cellosaurus cites itPubMed
From breast cancer immunobiology to her-2 DNA vaccine and autoimmune sequelae.Breast Dis2004Cellosaurus cites itPubMed
A novel orthotopic model of breast cancer metastasis to bone.Clin Exp Metastasis1999Cellosaurus cites itPubMed

1 to 10 of 13

See all 13 papers

Relatives6

RelationCell lineAccessionProblemSource
Parent66 [Mouse mammary tumor]CVCL_9722Cell lines
Derived from it66c14 luc1CVCL_E8TGCell lines
Derived from it66c14 luc2CVCL_E8THCell lines
Derived from it66c14 luc3CVCL_E8TICell lines
Derived from it66c14 luc4CVCL_E8TJCell lines
Derived from it66c14 luc5CVCL_E8TKCell lines

Cell banks0

None in this release.

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_9721

GET https://conductscience.org/api/cell-lines/v1/CVCL_9721/problems