ConductScience.org, home
Cell lines
API referenceFor AI assistants

Cell line · CVCL_A442

TMD8

Cancer cell line, Homo sapiens. Diffuse large B-cell lymphoma activated B-cell type. 33 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Download JSON
Cite this record

ConductScience Library. TMD8. Cell lines, record CVCL_A442. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_A442

On this page

Cell line

As Cellosaurus gives it.

Name
TMD8
Accession
CVCL_A442
RRID
RRID:CVCL_A442
Synonyms
TMD-8, Tokyo Medical and Dental university 8
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
62Y
Category
Cancer cell line
Diseases
Diffuse large B-cell lymphoma activated B-cell type (NCIt C36081); Diffuse large B-cell lymphoma (ORDO Orphanet_544)
Derived from
Bone marrow (in situ)
Entry created
2012-06-06
Entry updated
2026-03-31

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers33

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

PaperJournalYearHow we knowRetractedSource
Alternative oncogenic drivers and sensitivity to BTK inhibition in CRISPR/Cas gene-edited human DLBCL cell models.Blood Neoplasia2026Its Methods give the RRID and name the linePubMed
A 3D genome atlas of human tonsil and the role of loop extrusion in B cell somatic hypermutation.Science2026Its Methods give the RRID and name the linePubMed
Enhanced efficacy of a specific HDAC3 inhibitor in combination with 5-azacitidine against diffuse large B-cell lymphoma.Blood Neoplasia2026Its Methods give the RRID and name the linePubMed
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
The tropomyosin 3.1/3.2 inhibitor ATM-3507 alters B-cell actin dynamics and impairs the growth and motility of diffuse large B-cell lymphoma cell lines.Front Immunol2025Its Methods give the RRID and name the linePubMed
Blocking NRF2 Translation by Inhibition of Cap-Dependent Initiation Sensitizes Lymphoma Cells to Ferroptosis and CAR T-cell Immunotherapy.Cancer Res2025Its Methods give the RRID and name the linePubMed
DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response.Blood Cancer Discov2025Its Methods give the RRID and name the linePubMed
EZB-type diffuse large B-cell lymphoma cell lines have superior migration capabilities compared to MCD-type.Br J Haematol2024Its Methods give the RRID and name the linePubMed
Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC.Cell Commun Signal2024Its Methods give the RRID and name the linePubMed
IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma.Cancer Cell2024Its Methods give the RRID and name the linePubMed

1 to 10 of 33

See all 33 papers

Relatives14

RelationCell lineAccessionProblemSource
Derived from itHyCyte TMD8 hBTK_p.L528W_c.1583T>G cell lineCVCL_F4KACell lines
Derived from itTMD8-BTK-A428D-KI-1B4CVCL_E8IZCell lines
Derived from itTMD8-BTK-C481F-KICVCL_E8J0Cell lines
Derived from itTMD8-BTK-C481S-KI-1B3CVCL_E8J1Cell lines
Derived from itTMD8-BTK-C481S-KI-1C6CVCL_E8J2Cell lines
Derived from itTMD8-BTK-C481Y-KI-1A2CVCL_E8J3Cell lines
Derived from itTMD8-BTK-C481Y-KI-1B2CVCL_E8J4Cell lines
Derived from itTMD8-BTK-HiBiT-KI-1B1CVCL_E8J5Cell lines
Derived from itTMD8-BTK-L528W-KICVCL_E8J6Cell lines
Derived from itTMD8-BTK-T474I-KI-1A1CVCL_E8J7Cell lines

1 to 10 of 14

See all 14 relatives

Cell banks1

Cell bankCatalog numberStatus
CLS305729

Source CLS

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_A442

GET https://conductscience.org/api/cell-lines/v1/CVCL_A442/papers?page=2

API referenceFor AI assistants