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Cell line · CVCL_A590

NCI-N592

Cancer cell line, Homo sapiens. Lung small cell carcinoma. Cellosaurus records it as contaminated. 7 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. NCI-N592. Cell lines, record CVCL_A590. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_A590

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Cell line

As Cellosaurus gives it.

Name
NCI-N592
Accession
CVCL_A590
RRID
RRID:CVCL_A590
Synonyms
N592, N-592, NCI-H592, H592, H-592, NCIN592
Species
Homo sapiens (Human)
Sex
Male
Age at sampling
55Y
Category
Cancer cell line
Diseases
Lung small cell carcinoma (NCIt C4917); Small cell lung cancer (ORDO Orphanet_70573)
Derived from
Pleural effusion (metastatic)
Parent
NCI-H69 (CVCL_1579)
Entry created
2012-06-06
Entry updated
2025-04-10

Source Cellosaurus

Problems1

ProblemCellosaurus's note
ContaminatedShown to be a NCI-H69 derivative.

Papers7

PaperJournalYearHow we knowRetractedSource
Array comparative genomic hybridization-based characterization of genetic alterations in pulmonary neuroendocrine tumors.Proc Natl Acad Sci U S A2010Cellosaurus cites itPubMed
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.J Cancer Res Clin Oncol2001Cellosaurus cites itPubMed
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.J Cell Biochem Suppl1996Cellosaurus cites itPubMed
NCI-Navy Medical Oncology Branch cell line data base.J Cell Biochem Suppl1996Cellosaurus cites itPubMed
Neuromedin B is present in lung cancer cell lines.Cancer Res1992Cellosaurus cites itPubMed
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).Br J Cancer1989Cellosaurus cites itPubMed
Establishment and identification of small cell lung cancer cell lines having classic and variant features.Cancer Res1985Cellosaurus cites itPubMed

Relatives3

RelationCell lineAccessionProblemSource
ParentNCI-H69CVCL_1579Cell lines
Derived from itNCI-N592/IFN-gammaCVCL_E4CSHas a recorded problemCell lines
Derived from itNCI-N592/IL2CVCL_E4CTHas a recorded problemCell lines

Cell banks1

Cell bankCatalog numberStatus
ATCCCRL-5832Discontinued

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_A590

GET https://conductscience.org/api/cell-lines/v1/CVCL_A590/problems