Cell line · CVCL_B288

MC-38

Cancer cell line, Mus musculus. Mouse colon adenocarcinoma. 258 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. MC-38. Cell lines, record CVCL_B288. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_B288

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Cell line

As Cellosaurus gives it.

Name: MC-38
Accession: CVCL_B288
RRID: RRID:CVCL_B288
Synonyms: MCA-38, MCA 38, MCA38, MC38, MC-38 B/6, Mouse Colon 38, Murine Carcinoma-38, Colon-38, Colon 38, Colon38, C38
Species: Mus musculus (Mouse)
Sex: Female
Age at sampling: Age unspecified
Category: Cancer cell line
Diseases: Mouse colon adenocarcinoma (NCIt C120044)
Derived from: Colon (in situ)
Entry created: 2012-06-06
Entry updated: 2026-06-25

Source Cellosaurus

Problems1

Problem	Cellosaurus's note
Caution	The authors of PubMed=25434994 indicate that they have sequenced the mitochondrial genome of the 'rat' cell line MCA38. Their submitted DNA sequence (KM820832.1) is indeed a rat sequence but is labelled as originating from 'rat isolate 406'.

Source Cellosaurus

Papers258

Paper	Journal	Year	How we know	Source
PubMed 43000531	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed
PubMed 42999633	Immunotargets Ther	2026	Its Methods give the RRID and name the line	PubMed
IFNAR1 stabilization sustains CD8+ T cell persistence in IFN-high colorectal cancer liver metastases.	Sci Adv	2026	Its Methods give the RRID and name the line	PubMed
MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation-Associated Colorectal Cancer by Suppressing the STAT3-CCL2 Axis and TAM-Mediated Immunosuppression.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Loss of Lepr in Fibroblasts Drives Tumor Development by Promoting Macrophage Infiltration.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Liver-specific amino acid metabolism impacts on efficacy of cancer immunotherapy.	Oncogene	2026	Its Methods give the RRID and name the line	PubMed
Compartment-specific PPARδ activity controls the outcome of cancer-immune cell competition and immunotherapy efficacy.	Nat Immunol	2026	Its Methods give the RRID and name the line	PubMed
AIM2 in tregs restrains anti-PD-1 efficacy by reinforcing immune suppression in MC38 colorectal cancer.	iScience	2026	Its Methods give the RRID and name the line	PubMed
MIIP Inhibits Colorectal Cancer Progression by Modulating Neutrophils Infiltration and Neutrophil Extracellular Trap Formation.	Adv Sci (Weinh)	2026	Its Methods give the RRID and name the line	PubMed
Intravenously deliverable oncolytic virus VET3-TGI favorably alters the tumor microenvironment.	J Immunother Cancer	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 258

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Relatives71

Relation	Cell line	Accession	Source
Derived from it	EDITGENE Il4i1 Knockout MC-38 Cell Line	CVCL_F5BN	Cell lines
Derived from it	EDITGENE MC-38-CopGFP	CVCL_F6BE	Cell lines
Derived from it	EDITGENE MC-38-FLUC	CVCL_F5TS	Cell lines
Derived from it	EDITGENE MC38-Cas9	CVCL_F5PU	Cell lines
Derived from it	Genomeditech MC-38 H_AMHR2	CVCL_E6WA	Cell lines
Derived from it	Genomeditech MC-38 H_CD24	CVCL_E6WB	Cell lines
Derived from it	Genomeditech MC-38 H_CD274(PD-L1)	CVCL_E6WC	Cell lines
Derived from it	Genomeditech MC-38 H_CD47	CVCL_E6WD	Cell lines
Derived from it	Genomeditech MC-38 H_CEACAM5(CEA)	CVCL_E6WE	Cell lines
Derived from it	Genomeditech MC-38 H_CLDN18(isoform 2)	CVCL_E6WF	Cell lines

1 to 10 of 71

See all 71 relatives

Cell banks8

Cell bank	Catalog number	Status	Source
ABM	T8291		ABM
CLS	305223	Discontinued	Cellosaurus
EDITGENE	EDC00075		EDITGENE
Hysigen	TCM-C790		Hysigen
Kerafast	ENH204-FP		Kerafast
Millipore	SCC172		Millipore
NCI-DCTD	Colon 38		Cellosaurus
Ubigene	YC-A002		Ubigene

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_B288

GET https://conductscience.org/api/cell-lines/v1/CVCL_B288/papers?page=2

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