Cell line · CVCL_HD57
DLD-1 BRCA2(-/-)
Cancer cell line, Homo sapiens. Colon adenocarcinoma. 7 papers.
4 sourcescell-lines-2026-11-14-0.1.0
Cite this record
ConductScience Library. DLD-1 BRCA2(-/-). Cell lines, record CVCL_HD57. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_HD57
On this page
Cell line
As Cellosaurus gives it.
- Name
- DLD-1 BRCA2(-/-)
- Accession
- CVCL_HD57
- RRID
- RRID:CVCL_HD57
- Synonyms
- BRCA2 (-/-) DLD-1
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 67Y
- Category
- Cancer cell line
- Diseases
- Colon adenocarcinoma (NCIt C4349)
- Derived from
- Colon (in situ)
- Cell type
- Epithelial cell of colon
- Parent
- DLD-1 (CVCL_0248)
- Entry created
- 2016-12-01
- Entry updated
- 2024-12-19
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers7
1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| CIP2A recruits SLX4-MUS81-XPF in mitosis and protects against replication stress. | EMBO Rep | 2026 | Its Methods give the RRID and name the line | PubMed | |
| Preclinical synergistic effects when combining a radiolabelled HER2-targeting single domain antibody with PARP inhibitor Olaparib. | J Transl Med | 2025 | Its Methods give the RRID and name the line | PubMed | |
| BRCA2 deficiency and replication stress drive APOBEC3-Mediated genomic instability. | Nat Commun | 2025 | Its Methods give the RRID and name the line | PubMed | |
| Enhanced pharmacological activities of AKR1C3-activated prodrug AST-3424 in cancer cells with defective DNA repair. | Int J Cancer | 2025 | Its Methods give the RRID and name the line | PubMed | |
| PARG-deficient tumor cells have an increased dependence on EXO1/FEN1-mediated DNA repair. | EMBO J | 2024 | Its Methods give the RRID and name the line | PubMed | |
| The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability. | Cell Rep | 2021 | Its Methods give the RRID and name the line | PubMed | |
| A syngeneic variance library for functional annotation of human variation: application to BRCA2. | Cancer Res | 2008 | Cellosaurus cites it | PubMed |
Relatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| Parent | DLD-1 | CVCL_0248 |
Source Cell lines
Cell banks1
| Cell bank | Catalog number | Status |
|---|---|---|
| Horizon_Discovery | HD+105-007 |
Source Horizon_Discovery
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_HD57
GET https://conductscience.org/api/cell-lines/v1/CVCL_HD57/problems