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Cell line · CVCL_II76

HMC3

Transformed cell line, Homo sapiens. 43 papers.

4 sourcescell-lines-2026-11-14-0.1.0

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ConductScience Library. HMC3. Cell lines, record CVCL_II76. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_II76

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Cell line

As Cellosaurus gives it.

Name
HMC3
Accession
CVCL_II76
RRID
RRID:CVCL_II76
Synonyms
Human Microglia Clone 3, CHME-3, CHME3
Species
Homo sapiens (Human)
Sex
Sex unspecified
Age at sampling
8-10FW
Category
Transformed cell line
Derived from
Fetal brain (in situ)
Cell type
Microglial cell
Entry created
2016-12-01
Entry updated
2026-06-25

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers43

2 more articles give this line's RRID in its Methods without naming the line nearby, so they are not listed.

PaperJournalYearHow we knowRetractedSource
Low-Density Lipoprotein Receptor-Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation.Adv Sci (Weinh)2026Its Methods give the RRID and name the linePubMed
Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth.Cell2026Its Methods give the RRID and name the linePubMed
Modelling Ferroptosis in a Human Microglial Line by Sequential Exposure to Iron and GPX4 Inhibition.Oxid Med Cell Longev2026Its Methods give the RRID and name the linePubMed
IL-4-Primed Microglial Extracellular Vesicles Attenuate Rotenone-Induced Cell Death in SH-SY5Y Cells: A Contributory Role for miR-191-5p.ASN Neuro2026Its Methods give the RRID and name the linePubMed
Calcium signaling in human and mouse microglia exhibit differential susceptibility to phytocannabinoids.Cell Commun Signal2026Its Methods give the RRID and name the linePubMed
PARP1 rewires neuroinflammatory and redox metabolism associated with reactive neuroglia in neuropathic pain.Redox Biol2026Its Methods give the RRID and name the linePubMed
Progranulin deficiency in the brain activates an insulin signaling pathway that may promote neurodegeneration.iScience2026Its Methods give the RRID and name the linePubMed
3D Aerohydrogel Scaffolds for Brain Tissue Engineering and In Vitro Neuroscience.Chem Bio Eng2026Its Methods give the RRID and name the linePubMed
Discovery of a novel Nrf2 activator that modulates mitochondrial function in neurons by regulating DHRS3-Nrf2 interaction after ischemic stroke.Theranostics2026Its Methods give the RRID and name the linePubMed

1 to 10 of 43

See all 43 papers

Relatives3

RelationCell lineAccessionProblemSource
Derived from itHyCyte HMC3 stable cell line for hTFEB overexpressionCVCL_F4Q0Cell lines
Derived from itHyCyte HMC3 stable cell line for hZKSCAN3 overexpressionCVCL_F4QZCell lines
Derived from itUbigene HMC3 CLEC3B KOCVCL_D9WBCell lines

Cell banks4

Cell bankCatalog numberStatusSource
ATCCCRL-3304ATCC
CLS300102CLS
HysigenTCH-C399Hysigen
UbigeneYC-C131Ubigene

Data dates

The date of each source this release read.

Cellosaurus
2026-10-22
Cellosaurus
PubMed Central's articles
2026-11-12
PubMed Central's articles
Our copy of PubMed
2026-11-06
Our copy of PubMed

Sources 4

  • CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
  • PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
  • NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
  • PubMedNLM's terms
Each source's terms
  • CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
  • PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
  • NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
  • PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_II76

GET https://conductscience.org/api/cell-lines/v1/CVCL_II76/papers?page=2