Cell line · CVCL_RT21
H446/CDDP
Cancer cell line, Homo sapiens. Lung small cell carcinoma. 3 papers.
4 sourcescell-lines-2026-11-14-0.1.0
Cite this record
ConductScience Library. H446/CDDP. Cell lines, record CVCL_RT21. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_RT21
On this page
Cell line
As Cellosaurus gives it.
- Name
- H446/CDDP
- Accession
- CVCL_RT21
- RRID
- RRID:CVCL_RT21
- Synonyms
- H446/DDP
- Species
- Homo sapiens (Human)
- Sex
- Male
- Age at sampling
- 61Y
- Category
- Cancer cell line
- Diseases
- Lung small cell carcinoma (NCIt C4917); Small cell lung cancer (ORDO Orphanet_70573)
- Derived from
- Pleural effusion (metastatic)
- Parent
- NCI-H446 (CVCL_1562)
- Entry created
- 2018-03-05
- Entry updated
- 2025-04-10
Source Cellosaurus
Problems0
Cellosaurus records no problem for this cell line.
None in this release.
Papers3
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Analysis of novel microRNA targets in drug-sensitive and -insensitive small cell lung cancer cell lines. | Oncol Rep | 2016 | Cellosaurus cites it | PubMed | |
| Inhibition of proliferation and apoptosis induced by a Na+/H+ exchanger-1 (NHE-1) antisense gene on drug-resistant human small cell lung cancer cells. | Oncol Rep | 2009 | Cellosaurus cites it | PubMed | |
| [Involvement of bcl-2 in multidrug resistance in human small cell lung cancer cell subline H446/DDP]. | Zhonghua Jie He He Hu Xi Za Zhi | 2006 | Cellosaurus cites it | PubMed |
Relatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| Parent | NCI-H446 | CVCL_1562 |
Source Cell lines
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_RT21
GET https://conductscience.org/api/cell-lines/v1/CVCL_RT21/problems