Cell line · CVCL_Y019

HAP1

Cancer cell line, Homo sapiens. Chronic myelogenous leukemia, BCR-ABL1 positive. 87 papers.

4 sourcescell-lines-2026-11-14-0.1.0

Cite this record

ConductScience Library. HAP1. Cell lines, record CVCL_Y019. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_Y019

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Cell line

As Cellosaurus gives it.

Name: HAP1
Accession: CVCL_Y019
RRID: RRID:CVCL_Y019
Synonyms: HAP-1
Species: Homo sapiens (Human)
Sex: Male
Age at sampling: 40Y
Category: Cancer cell line
Diseases: Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt C3174); Chronic myeloid leukemia (ORDO Orphanet_521)
Derived from: Bone marrow (in situ)
Parent: KBM-7 (CVCL_A426)
Entry created: 2014-11-07
Entry updated: 2025-04-10

Source Cellosaurus

Problems0

Cellosaurus records no problem for this cell line.

None in this release.

Papers87

1 more article gives this line's RRID in its Methods without naming the line nearby, so it is not listed.

Paper	Journal	Year	How we know	Source
Targeting tankyrase scaffolding in the β-catenin destruction complex by PROTAC overcomes the limitation of catalytic inhibitors in colorectal cancer.	Elife	2026	Its Methods give the RRID and name the line	PubMed
A validated antibody toolbox for ALS research.	Elife	2026	Its Methods give the RRID and name the line	PubMed
A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation.	Nat Commun	2026	Its Methods give the RRID and name the line	PubMed
A guide to selecting high-performing antibodies for ARID1B (UniProt ID: Q8NFD5) for use in western blot and immunoprecipitation.	F1000Res	2026	Its Methods give the RRID and name the line	PubMed
A guide to selecting high-performing antibodies for Syntenin-1 (O00560) for use in western blot, immunoprecipitation, and immunofluorescence.	F1000Res	2026	Its Methods give the RRID and name the line	PubMed
MYDGF as a telomerase activator and therapeutic target for osteoarthritis.	Adv Biotechnol (Singap)	2026	Its Methods give the RRID and name the line	PubMed
Posaconazole mitigates α-amanitin-induced liver injury by inhibiting STT3B-mediated glycosylation and cellular uptake.	Front Pharmacol	2026	Its Methods give the RRID and name the line	PubMed
The regulation of protein phosphatase 4 by FBXO42 is required for cancer cell survival.	EMBO Rep	2026	Its Methods give the RRID and name the line	PubMed
Leukemia risk factor ARID5B coordinates HDAC-mediated transcriptional repression.	Nucleic Acids Res	2026	Its Methods give the RRID and name the line	PubMed
PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination-Mediated Chemoresistance.	Cancer Res	2026	Its Methods give the RRID and name the line	PubMed

1 to 10 of 87

See all 87 papers

Relatives7,169

Relation	Cell line	Accession	Source
Parent	KBM-7	CVCL_A426	Cell lines
Derived from it	EDITGENE AATK Knockout HAP1 Cell Line	CVCL_F5EA	Cell lines
Derived from it	EDITGENE ABCA1 Knockout HAP1 Cell Line	CVCL_F5EY	Cell lines
Derived from it	EDITGENE ACHE Knockout HAP1 Cell Line	CVCL_F5HP	Cell lines
Derived from it	EDITGENE ACSL3 Knockout HAP1 Cell Line	CVCL_F5DE	Cell lines
Derived from it	EDITGENE ACVR1B Knockout HAP1 Cell Line	CVCL_F5IB	Cell lines
Derived from it	EDITGENE ACVR2A Knockout HAP1 Cell Line	CVCL_F6IN	Cell lines
Derived from it	EDITGENE AKAP11 Knockout HAP1 Cell Line	CVCL_F5CK	Cell lines
Derived from it	EDITGENE ALOX12 Knockout HAP1 Cell Line	CVCL_F6G8	Cell lines
Derived from it	EDITGENE ANXA1 Knockout HAP1 Cell Line	CVCL_F6IS	Cell lines

1 to 10 of 7,169

See all 7,169 relatives

Cell banks1

Cell bank	Catalog number	Status
Horizon_Discovery	C631

Source Horizon_Discovery

Data dates

The date of each source this release read.

Cellosaurus: 2026-10-22; Cellosaurus
PubMed Central's articles: 2026-11-12; PubMed Central's articles
Our copy of PubMed: 2026-11-06; Our copy of PubMed

Sources 4

CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
PubMedNLM's terms

Each source's terms

CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
PubMedNLM's terms

Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.

For software

Read this cell line from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/cell-lines/v1/CVCL_Y019

GET https://conductscience.org/api/cell-lines/v1/CVCL_Y019/papers?page=2

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