Cell line · CVCL_ZZ16
MCF-7 TH
Cancer cell line, Homo sapiens. High grade ovarian serous adenocarcinoma. Cellosaurus records it as contaminated. 4 papers.
4 sourcescell-lines-2026-11-14-0.1.0
Cite this record
ConductScience Library. MCF-7 TH. Cell lines, record CVCL_ZZ16. Release cell-lines-2026-11-14-0.1.0, 14 Nov 2026. https://conductscience.org/library/cell-lines/CVCL_ZZ16
On this page
Cell line
As Cellosaurus gives it.
- Name
- MCF-7 TH
- Accession
- CVCL_ZZ16
- RRID
- RRID:CVCL_ZZ16
- Synonyms
- MCF-7/TH, MCF-7TH, MCF7/TH, MCF7TH, MCF7Th
- Species
- Homo sapiens (Human)
- Sex
- Female
- Age at sampling
- 64Y
- Category
- Cancer cell line
- Diseases
- High grade ovarian serous adenocarcinoma (NCIt C105555)
- Parent
- OVCAR-8 (CVCL_1629)
- Entry created
- 2020-10-29
- Entry updated
- 2024-12-19
Source Cellosaurus
Problems1
| Problem | Cellosaurus's note |
|---|---|
| Contaminated | Shown to be a OVCAR-8 derivative (PubMed=10995814). Originally thought to be a derivative of MCF-7. |
Source Cellosaurus
Papers4
| Paper | Journal | Year | How we know | Retracted | Source |
|---|---|---|---|---|---|
| Synergistic cytotoxicity of pyrazoloacridine with doxorubicin, etoposide, and topotecan in drug-resistant tumor cells. | Clin Cancer Res | 2004 | Cellosaurus cites it | PubMed | |
| Uncertain identity of doxorubicin-resistant MCF-7 cell lines expressing mutated p53. | J Natl Cancer Inst | 2000 | Cellosaurus cites it | PubMed | |
| Altered gene expression in drug-resistant human breast cancer cells. | Clin Cancer Res | 1997 | Cellosaurus cites it | PubMed | |
| Normal p53 status and function despite the development of drug resistance in human breast cancer cells. | Cell Growth Differ | 1995 | Cellosaurus cites it | PubMed |
Relatives1
| Relation | Cell line | Accession | Problem |
|---|---|---|---|
| Parent | OVCAR-8 | CVCL_1629 |
Source Cell lines
Cell banks0
None in this release.
Data dates
The date of each source this release read.
Sources 4
- CellosaurusCC BY 4.0, with credit to Cellosaurus (SIB)
- PubMed Central's articlesTitles shown only for CC0, CC BY and public domain articles
- NLM's PMC Article DatasetsCourtesy of NLM, which does not endorse this database
- PubMedNLM's terms
Each source's terms
- CellosaurusCC BY 4.0. Cellosaurus's README: "we have chosen to apply the Creative Commons Attribution 4.0 International (CC BY 4.0) license to Cellosaurus (https://creativecommons.org/licenses/by/4.0/). This means that you are free to copy and redistribute Cellosaurus in any medium or format. You can remix, transform, and build upon Cellosaurus for any purpose, even commercially. You must give appropriate credit, provide a link to the license, and indicate if changes were made." Copyright (c) CALIPHO group, SIB Swiss Institute of Bioinformatics. Read on 14 Nov 2026 at https://ftp.expasy.org/databases/cellosaurus/README
- PubMed Central's articlesEach article's own license. Its words show only under CC0, CC BY or public domain
- NLM's PMC Article DatasetsNLM's PMC Article Datasets on AWS, https://registry.opendata.aws/ncbi-pmc. Its terms: users "acknowledge NLM as the source of the data in a clear and conspicuous manner", do not use the PubMed Central wordmark or the PMC logo, do not "indicate or imply that NLM/NIH/HHS has endorsed" a product, and "only distribute data that are licensed for redistribution". Each article keeps its own license: https://pmc.ncbi.nlm.nih.gov/about/copyright/
- PubMedNLM's terms
Cellosaurus, SIB Swiss Institute of Bioinformatics, https://www.cellosaurus.org, CC BY 4.0. Its problem notes are given in its own words.
For software
Read this cell line from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/cell-lines/v1/CVCL_ZZ16
GET https://conductscience.org/api/cell-lines/v1/CVCL_ZZ16/problems