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Comparison · NCT00000620-d5d999ec

BP Trial: Intensive Control vs BP Trial: Standard Control: Stroke in the Blood Pressure Trial.

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. BP Trial: Intensive Control vs BP Trial: Standard Control: Stroke in the Blood Pressure Trial. Trial comparisons, record NCT00000620-d5d999ec. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00000620-d5d999ec

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.01520.0110.021wilson
Risk in group 20.02610.02050.0334wilson
Risk difference, group 1 minus group 2-0.0109-0.0193-0.0028newcombe hybrid score
Risk ratio, group 1 over group 20.5830.3880.875log
Odds ratio, group 1 over group 20.5760.3810.872log
Number needed to treat, for one fewer participant with the outcome on BP Trial: Intensive Control than on BP Trial: Standard Control91.651.9358from the risk difference interval

Groups2

Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1BP Trial: Intensive Control
Open label administration of anti-hypertensive agents to reduce and maintain systolic blood pressure (SBP) level to \<120 mmHg. Anti-hypertensive agents include multiple anti-hypertensive medications as needed to reach Blood Pressure Trial arm-specific goals.
362,363OG000
Group 2BP Trial: Standard Control
Open label administration of multiple anti-hypertensive agents to maintain SBP level to \<140 mm Hg. Anti-hypertensive agents include multiple anti-hypertensive medications as needed to reach Blood Pressure Trial arm-specific goals.
622,371OG001

Outcome

Type
SECONDARY
Title
Stroke in the Blood Pressure Trial.
Description
Time to first occurrence of nonfatal or fatal stroke among participants in the BP Trial.
Time frame
4.7 years
Population
The population analyzed included all participants randomized and was performed by intention to treat with right-censoring of participants who did not complete follow-up prior to occurrence of stroke.

Source ClinicalTrials.gov

Trial

Title
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
NCT number
NCT00000620
Phases
PHASE3
Conditions
Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Type 2, Diabetes Mellitus, Coronary Disease
Interventions
Anti-hyperglycemic Agents, Anti-hypertensive Agents, Blinded fenofibrate or placebo plus simvastatin
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Results first posted
2014-09-15

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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