Comparison · NCT00009945-deaths
Clodronate vs Placebo: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Clodronate vs Placebo: deaths from any cause. Trial comparisons, record NCT00009945-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00009945-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0031 | 0.00133 | 0.00724 | wilson | |
| Risk in group 2 | 0.00739 | 0.00423 | 0.0129 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00429 | -0.0101 | 0.000915 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.42 | 0.148 | 1.19 | log | |
| Odds ratio, group 1 over group 2 | 0.418 | 0.147 | 1.19 | log | |
| Number needed to treat, for one fewer death from any cause on Clodronate than on Placebo | 233 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Clodronate | Clodronate | 5 | 1,612 | EG000 |
| Group 2 | Placebo | Placebo | 12 | 1,623 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Clodronate With or Without Chemotherapy and/or Hormonal Therapy in Treating Women With Stage I or Stage II Breast Cancer
- NCT number
- NCT00009945
- Phases
- PHASE3
- Conditions
- Breast Cancer
- Interventions
- clodronate, placebo
- Lead sponsor
- NSABP Foundation Inc
- Results first posted
- 2017-11-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00009945?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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