Comparison · NCT00010803-57cceaa8
Ginkgo Biloba vs Placebo: Number of Participants With Incident Dementia
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Ginkgo Biloba vs Placebo: Number of Participants With Incident Dementia. Trial comparisons, record NCT00010803-57cceaa8. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00010803-57cceaa8
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.179 | 0.161 | 0.199 | wilson | |
| Risk in group 2 | 0.161 | 0.144 | 0.181 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0179 | -0.00876 | 0.0445 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.11 | 0.95 | 1.3 | log | |
| Odds ratio, group 1 over group 2 | 1.13 | 0.94 | 1.37 | log | |
| Number needed to treat, for one more participant with the outcome on Ginkgo Biloba than on Placebo | 56 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ginkgo Biloba | 120 mg twice daily, total 240 mg | 277 | 1,545 | OG000 |
| Group 2 | Placebo | Placebo 1 pill twice a day | 246 | 1,524 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants With Incident Dementia
- Description
All cause dementia based on DSM-IV criteria as determined by an expert panel of clinicians using an adjudication process. A full neuropsychological battery was administered annually, or at 6 month visit if there was a diagnosis of dementia or initiation of medication for dementia by private physician, or change in Modified Mini Mental State Exam (3MSE), Clinical Dementia Rating (CDR), or Alzheimer Disease Assessment Scale (ADAS-Cog). Decline on tests scores based on an algorithm resulted in a neurological exam and brain imaging. These data were used in the adjudication process.
- Time frame
- Brief neuropsychological testing every 6 months, detailed testing annually, average 6.1 years follow up
- Population
- Subjects developing incident dementia during trial in each group, intention to treat (ITT).
Source ClinicalTrials.gov
Trial
- Title
- Ginkgo Biloba Prevention Trial in Older Individuals
- NCT number
- NCT00010803
- Phases
- PHASE3
- Conditions
- Dementia, Alzheimer's Disease
- Interventions
- Ginkgo biloba, Placebo
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- Results first posted
- 2010-09-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00010803?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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