Comparison · NCT00059332-dc72cac0
Normal Saline vs Magnesium Sulfate: Modified Rankin Score of 0 or 1
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Normal Saline vs Magnesium Sulfate: Modified Rankin Score of 0 or 1. Trial comparisons, record NCT00059332-dc72cac0. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00059332-dc72cac0
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.369 | 0.337 | 0.402 | wilson | |
| Risk in group 2 | 0.365 | 0.334 | 0.398 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00369 | -0.042 | 0.0494 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.01 | 0.892 | 1.14 | log | |
| Odds ratio, group 1 over group 2 | 1.02 | 0.834 | 1.24 | log | |
| Number needed to treat, for one more participant with the outcome on Normal Saline than on Magnesium Sulfate | 271 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Normal Saline | Normal Saline: Paramedics initiate a loading dose of placebo normal saline IV over 15 minutes, followed after hospital arrival by a maintenance infusion of placebo normal saline IV over 24 hours. | 311 | 843 | OG000 |
| Group 2 | Magnesium Sulfate | Magnesium Sulfate: Paramedics initiate a loading dose of 4 grams magnesium sulfate IV over 15 minutes, followed after hospital arrival by a maintenance infusion of 16 grams magnesium sulfate IV over 24 hours. | 313 | 857 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Modified Rankin Score of 0 or 1
- Description
- Minimal or no disability based on the modified Rankin score
- Time frame
- 3 months
- Population
Source ClinicalTrials.gov
Trial
- Title
- Field Administration of Stroke Therapy - Magnesium (FAST-MAG) Trial
- NCT number
- NCT00059332
- Phases
- PHASE3
- Conditions
- Cerebrovascular Accident
- Interventions
- Magnesium Sulfate, Normal Saline
- Lead sponsor
- Jeffrey L. Saver
- Results first posted
- 2015-08-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00059332?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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