Comparison · NCT00064753-0ec673ca
High Dose Multivitamin vs Low Dose Multivitamin: Fatal/Non-fatal Myocardial Infarction (MI)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. High Dose Multivitamin vs Low Dose Multivitamin: Fatal/Non-fatal Myocardial Infarction (MI). Trial comparisons, record NCT00064753-0ec673ca. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00064753-0ec673ca
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0438 | 0.0357 | 0.0535 | wilson | |
| Risk in group 2 | 0.0419 | 0.034 | 0.0514 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0019 | -0.0106 | 0.0144 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.05 | 0.783 | 1.4 | log | |
| Odds ratio, group 1 over group 2 | 1.05 | 0.774 | 1.42 | log | |
| Number needed to treat, for one more participant with the outcome on High Dose Multivitamin than on Low Dose Multivitamin | 525 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | High Dose Multivitamin | Multivitamin with increased folic acid, vitamin B6 and vitamin B12~High Dose Multivitamin: Vitamin B6 (Pyridoxine HCl): 50 mg Folic acid: 5.0 mg Vitamin B12: 1.0 mg Vitamin B1 (Thiamine HNO3): 1.5 mg Vitamin B2 (Riboflavin): 1.5 mg Vitamin C (Ascorbic Acid): 60 mg d-Biotin: 300 mcg Niacinamide: 20 mg Pantothenic Acid Calcium Pantothenate): 10 mg | 90 | 2,056 | OG000 |
| Group 2 | Low Dose Multivitamin | Multivitamin devoid of folic acid and with EAR amounts of vitamin B6 and vitamin B12~Low Dose Multivitamin: Vitamin B6 (Pyridoxine HCl): 1.4 mg Folic acid: 0.0 mg Vitamin B12: 2.0 mcg Vitamin B1 (Thiamine HNO3): 1.5 mg Vitamin B2 (Riboflavin): 1.5 mg Vitamin C (Ascorbic Acid): 60 mg d-Biotin: 300 mcg Niacinamide: 20 mg Pantothenic Acid Calcium Pantothenate): 10 mg | 86 | 2,054 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Fatal/Non-fatal Myocardial Infarction (MI)
- Description
- censored at 3 months after return to dialysis
- Time frame
- Up to 6 years (mean 4 years)
- Population
Source ClinicalTrials.gov
Trial
- Title
- Folic Acid for Vascular Outcome Reduction In Transplantation (FAVORIT)
- NCT number
- NCT00064753
- Phases
- PHASE2, PHASE3
- Conditions
- Chronic Kidney Disease, Cardiovascular Disease, Death
- Interventions
- High Dose Multivitamin, Low Dose Multivitamin
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Results first posted
- 2015-11-26
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00064753?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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