Comparison · NCT00081653-sae
Ibandronate 100 mg vs Ibandronate 150 mg: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Ibandronate 100 mg vs Ibandronate 150 mg: serious adverse events. Trial comparisons, record NCT00081653-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00081653-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.19 | 0.153 | 0.234 | wilson | |
| Risk in group 2 | 0.194 | 0.156 | 0.238 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00396 | -0.0616 | 0.0537 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.98 | 0.726 | 1.32 | log | |
| Odds ratio, group 1 over group 2 | 0.975 | 0.672 | 1.41 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on Ibandronate 100 mg than on Ibandronate 150 mg | 252 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Ibandronate 100 mg | 100 mg ibandronate PO monthly and monthly oral placebo (corresponding to the 150 mg tablet) | 68 | 358 | EG000 |
| Group 2 | Ibandronate 150 mg | 150 mg ibandronate PO monthly and monthly oral placebo (corresponding to the 100 mg tablet) | 70 | 361 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- Adverse events were recorded from the date of informed consent until 15 days after the final visit at 36 months.
Source ClinicalTrials.gov
Trial
- Title
- A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Previously Treated With Bonviva
- NCT number
- NCT00081653
- Phases
- PHASE4
- Conditions
- Post-Menopausal Osteoporosis
- Interventions
- ibandronate [Bonviva/Boniva], ibandronate [Bonviva/Boniva]
- Lead sponsor
- Hoffmann-La Roche
- Results first posted
- 2009-07-21
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00081653?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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