Comparison · NCT00083174-f1e4d7bb
Randomization Period: Exemestane vs Randomization Period: Placebo: Incidence of Clinically Relevant Cardiac Events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Randomization Period: Exemestane vs Randomization Period: Placebo: Incidence of Clinically Relevant Cardiac Events. Trial comparisons, record NCT00083174-f1e4d7bb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00083174-f1e4d7bb
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0473 | 0.0393 | 0.0569 | wilson | |
| Risk in group 2 | 0.0494 | 0.0412 | 0.0591 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00206 | -0.0147 | 0.0106 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.958 | 0.739 | 1.24 | log | |
| Odds ratio, group 1 over group 2 | 0.956 | 0.728 | 1.26 | log | |
| Number needed to treat, for one fewer participant with the outcome on Randomization Period: Exemestane than on Randomization Period: Placebo | 486 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Randomization Period: Exemestane | one 25 mg tablet daily in am | 106 | 2,240 | OG000 |
| Group 2 | Randomization Period: Placebo | one tablet daily in am | 111 | 2,248 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Incidence of Clinically Relevant Cardiac Events
- Description
- Events including myocardial infarctions and angina requiring percutaneous transluminal coronary angioplasty or coronary artery bypass graft, fatal and nonfatal strokes and all vascular deaths
- Time frame
- During protocol treatment in randomization period (up to 5 years)
- Population
- Women who received treatment during randomization period
Source ClinicalTrials.gov
Trial
- Title
- Exemestane in Preventing Cancer in Postmenopausal Women at Increased Risk of Developing Breast Cancer
- NCT number
- NCT00083174
- Phases
- PHASE3
- Conditions
- Breast Cancer
- Interventions
- exemestane
- Lead sponsor
- NCIC Clinical Trials Group
- Results first posted
- 2013-05-20
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00083174?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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