Aspirin + Extended Release Dipyridamole vs Clopidogrel: Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Antiplatelet Comparison Only)
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.09 | 0.0846 | 0.0957 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0885 | 0.0831 | 0.0941 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | 0.00151 | -0.00633 | 0.00935 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 1.02 | 0.932 | 1.11 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 1.02 | 0.925 | 1.12 | log | ClinicalTrials.gov | |
| Number needed to treat, for one more participant with the outcome on Aspirin + Extended Release Dipyridamole than on Clopidogrel | 663 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | Aspirin + Extended Release Dipyridamole | Consists of patients in the two treatment groups: ASA+ERDP + telmisartan and ASA+ERDP + placebo | 916 | 10,181 | OG000 | ClinicalTrials.gov |
| Group 2 | Clopidogrel | Consists of patients in the two treatment groups: Clopidogrel + telmisartan and Clopidogrel + placebo | 898 | 10,151 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | Number of Patients With First Recurrent Stroke of Any Type, Fatal or Nonfatal (Antiplatelet Comparison Only) | ClinicalTrials.gov |
| Description | ClinicalTrials.gov | |
| Time frame | time since randomization; follow-up period is 1.5 to 4.4 years | ClinicalTrials.gov |
| Population | Patients were analyzed as randomized and were included in the analysis until final patient contact regardless of whether they were still on treatment. | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | PRoFESS - Prevention Regimen For Effectively Avoiding Second Strokes | ClinicalTrials.gov |
| NCT number | NCT00153062 | ClinicalTrials.gov |
| Phases | PHASE4 | ClinicalTrials.gov |
| Conditions | Stroke | ClinicalTrials.gov |
| Interventions | Aggrenox, Aggrenox, Clopidogrel placebo, Clopidogrel placebo, Micardis, Micardis, Aggrenox placebo, Aggrenox placebo, Clopidogrel, Clopidogrel, Micardis placebo, Micardis placebo | ClinicalTrials.gov |
| Lead sponsor | Boehringer Ingelheim | ClinicalTrials.gov |
| Results first posted | 2009-09-02 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT00153062?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.