Comparison · NCT00238420-e0d9b87d
HER2+ :RT, Paclitaxel, and Trastuzumab vs HER2- :RT and Paclitaxel: Treatment Completion
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. HER2+ :RT, Paclitaxel, and Trastuzumab vs HER2- :RT and Paclitaxel: Treatment Completion. Trial comparisons, record NCT00238420-e0d9b87d. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00238420-e0d9b87d
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.619 | 0.409 | 0.792 | wilson | |
| Risk in group 2 | 0.723 | 0.582 | 0.831 | wilson | |
| Risk difference, group 1 minus group 2 | -0.104 | -0.34 | 0.119 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.856 | 0.586 | 1.25 | log | |
| Odds ratio, group 1 over group 2 | 0.621 | 0.209 | 1.84 | log | |
| Number needed to treat, for one fewer participant with the outcome on HER2+ :RT, Paclitaxel, and Trastuzumab than on HER2- :RT and Paclitaxel | 9.58 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | HER2+ :RT, Paclitaxel, and Trastuzumab | Paclitaxel and trastuzumab chemotherapy with concurrent with radiation therapy | 13 | 21 | OG000 |
| Group 2 | HER2- :RT and Paclitaxel | Paclitaxel chemotherapy concurrent with radiation therapy | 34 | 47 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Treatment Completion
- Description
- The number of patients within each group who completed all elements of protocol treatment are reported.
- Time frame
- From registration to end of treatment; up to 64 days.
- Population
- All eligible patients who started study treatment
Source ClinicalTrials.gov
Trial
- Title
- Paclitaxel and Radiation Therapy With or Without Trastuzumab in Treating Patients Who Have Undergone Surgery for Bladder Cancer
- NCT number
- NCT00238420
- Phases
- PHASE1, PHASE2
- Conditions
- Bladder Urothelial Carcinoma, Stage I Bladder Cancer AJCC v6 and v7, Stage II Bladder Cancer AJCC v6 and v7, Stage III Bladder Cancer AJCC v6 and v7
- Interventions
- Paclitaxel, Radiation Therapy, Trastuzumab
- Lead sponsor
- National Cancer Institute (NCI)
- Results first posted
- 2016-05-23
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00238420?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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