Comparison · NCT00240331-54905608
Rosuvastatin 10mg vs Placebo: Number of Randomised Participants That Experienced a Procedure as a Result of Stenosis or Thrombosis of the Vascular Access (Arteriovenous (AV) Fistulas and Grafts Only) for Haemodialysis.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Rosuvastatin 10mg vs Placebo: Number of Randomised Participants That Experienced a Procedure as a Result of Stenosis or Thrombosis of the Vascular Access (Arteriovenous (AV) Fistulas and Grafts Only) for Haemodialysis. Trial comparisons, record NCT00240331-54905608. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00240331-54905608
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.281 | 0.258 | 0.305 | wilson | |
| Risk in group 2 | 0.26 | 0.238 | 0.284 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0207 | -0.0124 | 0.0537 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.08 | 0.955 | 1.22 | log | |
| Odds ratio, group 1 over group 2 | 1.11 | 0.939 | 1.31 | log | |
| Number needed to treat, for one more participant with the outcome on Rosuvastatin 10mg than on Placebo | 48.4 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Rosuvastatin 10mg | Rosuvastatin 10 mg oral tablets | 390 | 1,389 | OG000 |
| Group 2 | Placebo | Matching placebo | 360 | 1,384 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Randomised Participants That Experienced a Procedure as a Result of Stenosis or Thrombosis of the Vascular Access (Arteriovenous (AV) Fistulas and Grafts Only) for Haemodialysis.
- Description
- Time frame
- Events were reported continuously during the study. Duration of follow-up ranged from 1 day to 5.6 years
- Population
Source ClinicalTrials.gov
Trial
- Title
- AURORA: Crestor 10mg Versus Placebo in Subjects With End-stage Renal Disease (ESRD)
- NCT number
- NCT00240331
- Phases
- PHASE3
- Conditions
- Renal Failure
- Interventions
- 10mg Rosuvastatin, Placebo
- Lead sponsor
- AstraZeneca
- Results first posted
- 2009-11-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00240331?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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