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Comparison · NCT00240331-9a62b813

Rosuvastatin 10mg vs Placebo: Number of Randomised Participants With a Major Cardiovascular Event or That Died From Any Known Cause

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

2 sourcestrial-comparisons-2026-03-23-0.1.0

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ConductScience Library. Rosuvastatin 10mg vs Placebo: Number of Randomised Participants With a Major Cardiovascular Event or That Died From Any Known Cause. Trial comparisons, record NCT00240331-9a62b813. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00240331-9a62b813

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Measures6

Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.

MeasureValue95% interval, lower95% interval, upperMethodNote
Risk in group 10.4420.4160.468wilson
Risk in group 20.4660.440.492wilson
Risk difference, group 1 minus group 2-0.024-0.0610.0131newcombe hybrid score
Risk ratio, group 1 over group 20.9490.8741.03log
Odds ratio, group 1 over group 20.9080.7821.05log
Number needed to treat, for one fewer participant with the outcome on Rosuvastatin 10mg than on Placebo41.7from the risk difference intervalthe interval includes no difference

Groups2

Group 2 names the comparator: placebo.

GroupTitleDescriptionWith the outcomeAnalysedClinicalTrials.gov code
Group 1Rosuvastatin 10mgRosuvastatin 10 mg oral tablets6141,389OG000
Group 2PlaceboMatching placebo6451,384OG001

Outcome

Type
SECONDARY
Title
Number of Randomised Participants With a Major Cardiovascular Event or That Died From Any Known Cause
Description
Time frame
Events were reported continuously during the study. Duration of follow-up ranged from 1 day to 5.6 years
Population

Source ClinicalTrials.gov

Trial

Title
AURORA: Crestor 10mg Versus Placebo in Subjects With End-stage Renal Disease (ESRD)
NCT number
NCT00240331
Phases
PHASE3
Conditions
Renal Failure
Interventions
10mg Rosuvastatin, Placebo
Lead sponsor
AstraZeneca
Results first posted
2009-11-04

Source ClinicalTrials.gov

Source

Release
trial-comparisons-2026-03-23-0.1.0
Release manifest SHA-256
f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
AACT copy
2026-03-23
Tables read
outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet

Source ClinicalTrials.gov

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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