Comparison · NCT00274261-sae
C31G vs Conceptrol: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. C31G vs Conceptrol: serious adverse events. Trial comparisons, record NCT00274261-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00274261-sae
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.012 | 0.00651 | 0.0219 | wilson | |
| Risk in group 2 | 0.0214 | 0.0123 | 0.0371 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00947 | -0.026 | 0.00401 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.558 | 0.243 | 1.28 | log | |
| Odds ratio, group 1 over group 2 | 0.553 | 0.237 | 1.29 | log | |
| Number needed to treat, for one fewer participant with a serious adverse event on C31G than on Conceptrol | 106 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | C31G | C31G vaginal gel contains 35mg (1% concentration) of C31G in 3.5 mL volume of gel | 10 | 836 | EG000 |
| Group 2 | Conceptrol | Conceptrol® Vaginal gel contains 100mg (4% concentration) of nonoxynol-9 (N-9) in 2.5mL volume of gel. | 12 | 560 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
Source ClinicalTrials.gov
Trial
- Title
- Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®
- NCT number
- NCT00274261
- Phases
- PHASE3
- Conditions
- Pregnancy
- Interventions
- C31G, nonoxynol-9 (N-9)
- Lead sponsor
- Premier Research
- Results first posted
- 2013-06-06
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00274261?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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