Comparison · NCT00330863-e25ca1bb
Injectable vs Oral: Number of Patients Discontinuing From the Study
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Injectable vs Oral: Number of Patients Discontinuing From the Study. Trial comparisons, record NCT00330863-e25ca1bb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00330863-e25ca1bb
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.529 | 0.451 | 0.607 | wilson | |
| Risk in group 2 | 0.526 | 0.447 | 0.604 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0031 | -0.108 | 0.114 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.01 | 0.813 | 1.24 | log | |
| Odds ratio, group 1 over group 2 | 1.01 | 0.646 | 1.59 | log | |
| Number needed to treat, for one more participant with the outcome on Injectable than on Oral | 323 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Injectable | Participants assigned to receive long-acting injectable risperidone~Risperidone microspheres: Minimum dose is 12.5 mg every 2 weeks. Maximum dose is 75 mg every 2 weeks. | 81 | 153 | OG000 |
| Group 2 | Oral | Participants assigned to receive oral atypical antipsychotic medication~Risperidone: Target dose is 4 mg/day.~Olanzapine: Target dose is 15 mg/day.~Quetiapine: Target dose is 600 mg/day.~Ziprasidone: Target dose is 120 mg/day.~Aripiprazole: Target dose is 20 mg/day.~Paliperidone: Target dose is 6 mg/day. | 80 | 152 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients Discontinuing From the Study
- Description
- Time frame
- Measured throughout study up to 30 months
- Population
Source ClinicalTrials.gov
Trial
- Title
- Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy
- NCT number
- NCT00330863
- Phases
- PHASE4
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- Risperidone microspheres, Risperidone, Olanzapine, Quetiapine, Ziprasidone, Aripiprazole, Paliperidone
- Lead sponsor
- Northwell Health
- Results first posted
- 2018-07-10
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00330863?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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