Comparison · NCT00347776-bd6bf3dc
Intervention vs Control: Recurrent Trichiasis in Tetracycline and Azithromycin Groups
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Intervention vs Control: Recurrent Trichiasis in Tetracycline and Azithromycin Groups. Trial comparisons, record NCT00347776-bd6bf3dc. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00347776-bd6bf3dc
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.064 | 0.0503 | 0.0813 | wilson | |
| Risk in group 2 | 0.093 | 0.0702 | 0.122 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0289 | -0.0612 | -0.000388 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.689 | 0.477 | 0.995 | log | |
| Odds ratio, group 1 over group 2 | 0.668 | 0.447 | 0.996 | log | |
| Number needed to treat, for one fewer participant with the outcome on Intervention than on Control | 34.6 | 16.3 | 2,580 | from the risk difference interval |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Intervention | The two azithromycin groups combined~Antibiotic: Oral Azithromycin | 62 | 968 | OG001 |
| Group 2 | Control | Topical tetracycline~Antibiotic:Topical tetracycline | 45 | 484 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Recurrent Trichiasis in Tetracycline and Azithromycin Groups
- Description
- Recurrence of trichiasis : Clinical assessment was done by looking for one or more eye lashes touching globe or evidence of epilation.
- Time frame
- Primary outcome assessed at 2 weeks,1.5 months, 6 months and 12 months post-surgery
- Population
- Recurrence rates (expressed as person-years) in the tetracycline arm was compared with the 2 azithromycin arms combined (483+ 485= 968 participants)
Source ClinicalTrials.gov
Trial
- Title
- Study of Azithromycin to Prevent Recurrent Trichiasis Following Surgery in Ethiopia
- NCT number
- NCT00347776
- Phases
- PHASE4
- Conditions
- Trichiasis
- Interventions
- azithromycin, topical tetracycline
- Lead sponsor
- Johns Hopkins University
- Results first posted
- 2017-08-07
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00347776?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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