Comparison · NCT00358579-13d12561
Adrenaline vs Vasopressin: Survival to Admission.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Adrenaline vs Vasopressin: Survival to Admission. Trial comparisons, record NCT00358579-13d12561. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00358579-13d12561
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.167 | 0.132 | 0.21 | wilson | |
| Risk in group 2 | 0.222 | 0.183 | 0.267 | wilson | |
| Risk difference, group 1 minus group 2 | -0.0548 | -0.112 | 0.00298 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.753 | 0.558 | 1.02 | log | |
| Odds ratio, group 1 over group 2 | 0.704 | 0.485 | 1.02 | log | |
| Number needed to treat, for one fewer participant with the outcome on Adrenaline than on Vasopressin | 18.3 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Adrenaline | 1 mg Intravenous Adrenaline, administered as the first drug upon cardiac arrest patient's arrival at the Emergency Department | 59 | 353 | OG000 |
| Group 2 | Vasopressin | 40 IU Intravenous Vasopressin, administered as the first drug upon cardiac arrest patient's arrival at the Emergency Department | 83 | 374 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Survival to Admission.
- Description
Survival to admission is defined as the presence of pulse on admission to hospital (discharged from Emergency Department and admitted to Intensive Care Units /wards). This measures the number of participants with pulse and who were admitted to hospital.
- Time frame
- No specific time frame. Survival to admission refers to sustained return of spontaneous circulation until admission and transfer of care to Intensive Care Units /wards
- Population
Source ClinicalTrials.gov
Trial
- Title
- Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest
- NCT number
- NCT00358579
- Phases
- PHASE3
- Conditions
- Cardiac Arrest
- Interventions
- Adrenaline, Vasopressin
- Lead sponsor
- Singapore General Hospital
- Results first posted
- 2011-08-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00358579?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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