Comparison · NCT00358579-ba2ed389
Adrenaline vs Vasopressin: Survival to Hospital Discharge.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Adrenaline vs Vasopressin: Survival to Hospital Discharge. Trial comparisons, record NCT00358579-ba2ed389. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00358579-ba2ed389
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0227 | 0.0115 | 0.0441 | wilson | |
| Risk in group 2 | 0.0294 | 0.0165 | 0.0519 | wilson | |
| Risk difference, group 1 minus group 2 | -0.00675 | -0.0318 | 0.0183 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.771 | 0.314 | 1.89 | log | |
| Odds ratio, group 1 over group 2 | 0.765 | 0.304 | 1.93 | log | |
| Number needed to treat, for one fewer participant with the outcome on Adrenaline than on Vasopressin | 148 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Adrenaline | 1 mg Intravenous Adrenaline, administered as the first drug upon cardiac arrest patient's arrival at the Emergency Department | 8 | 353 | OG000 |
| Group 2 | Vasopressin | 40 IU Intravenous Vasopressin, administered as the first drug upon cardiac arrest patient's arrival at the Emergency Department | 11 | 374 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Survival to Hospital Discharge.
- Description
Survival to hospital discharge is defined as the patient leaving the hospital alive or survival to 30 days post cardiac arrest,whichever came first. This therefore measures the number of participants who was discharged alive or survived to 30 days post cardiac arrest, whichever came first.
- Time frame
- at 30 days post arrest
- Population
Source ClinicalTrials.gov
Trial
- Title
- Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest
- NCT number
- NCT00358579
- Phases
- PHASE3
- Conditions
- Cardiac Arrest
- Interventions
- Adrenaline, Vasopressin
- Lead sponsor
- Singapore General Hospital
- Results first posted
- 2011-08-09
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00358579?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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