Comparison · NCT00401726-88ddfaeb
Venlafaxine Extended Release (ER) vs Venlafaxine Extended Release (ER) Plus Dialogues: Number of Patients Compliant With Therapy
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Venlafaxine Extended Release (ER) vs Venlafaxine Extended Release (ER) Plus Dialogues: Number of Patients Compliant With Therapy. Trial comparisons, record NCT00401726-88ddfaeb. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00401726-88ddfaeb
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.976 | 0.949 | 0.989 | wilson | |
| Risk in group 2 | 0.971 | 0.941 | 0.986 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00567 | -0.0252 | 0.0382 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.01 | 0.977 | 1.04 | log | |
| Odds ratio, group 1 over group 2 | 1.25 | 0.413 | 3.77 | log | |
| Number needed to treat, for one more participant with the outcome on Venlafaxine Extended Release (ER) than on Venlafaxine Extended Release (ER) Plus Dialogues | 176 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Venlafaxine Extended Release (ER) | 75-225 mg per day | 248 | 254 | OG000 |
| Group 2 | Venlafaxine Extended Release (ER) Plus Dialogues | Venlafaxine ER 75-225 mg per day plus Dialogues Time to Talk program (Dialogues). Dialogues is a patient management program designed to reinforce physician treatment efforts, provide feedback to treating physicians and encourage better physician-patient communication. | 232 | 239 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Patients Compliant With Therapy
- Description
Patient compliance with therapy was assessed using a Medical Adherence Questionnaire (MAQ). MAQ consisted of 5 levels of compliance with taking medicine: Never miss, Sometimes miss, Miss half of the time, Miss most of the time, Always miss. Compliance with therapy was defined as a response of Never miss or Sometimes miss.
- Time frame
- 112 days
- Population
The analysis population was the Modified Intent to Treat population, which included all patients who received a prescription and had at least 1 post-baseline efficacy evaluation; last observation carried forward.
Source ClinicalTrials.gov
Trial
- Title
- Open-Label, Randomized Study Evaluating Treatment With Venlafaxine Extended-Release Plus Dialogues Time to Talk Program
- NCT number
- NCT00401726
- Phases
- PHASE4
- Conditions
- Depressive Disorder, Major
- Interventions
- Venlafaxine ER, Dialogues Time to Talk Program
- Lead sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
- Results first posted
- 2010-06-29
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00401726?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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