Comparison · NCT00418314-9c19f77f
QuickOpt (Treatment) vs Control: All-cause, Cardiovascular and Heart Failure Mortality;
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. QuickOpt (Treatment) vs Control: All-cause, Cardiovascular and Heart Failure Mortality;. Trial comparisons, record NCT00418314-9c19f77f. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00418314-9c19f77f
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0539 | 0.0404 | 0.0716 | wilson | |
| Risk in group 2 | 0.0507 | 0.0377 | 0.0679 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0032 | -0.0186 | 0.0251 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.06 | 0.704 | 1.6 | log | |
| Odds ratio, group 1 over group 2 | 1.07 | 0.691 | 1.65 | log | |
| Number needed to treat, for one more participant with the outcome on QuickOpt (Treatment) than on Control | 313 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: control.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | QuickOpt (Treatment) | Frequent optimization using QuickOpt to optimize the AV/PV and VV Delays. | 44 | 816 | OG000 |
| Group 2 | Control | Empiric programming or one-time optimization using a non-IEGM method. | 42 | 828 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- All-cause, Cardiovascular and Heart Failure Mortality;
- Description
- Time frame
- 12 months
- Population
- Per protocol
Source ClinicalTrials.gov
Trial
- Title
- FREEDOM - A Frequent Optimization Study Using the QuickOpt Method
- NCT number
- NCT00418314
- Phases
- NA
- Conditions
- Cardiac Arrhythmias, Heart Failure
- Interventions
- Control, QuickOpt
- Lead sponsor
- Abbott Medical Devices
- Results first posted
- 2016-02-04
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00418314?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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