Comparison · NCT00418457-1ec6fdd3
General Anesthesia and Opioid vs Regional Analgesia and Propofol: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. General Anesthesia and Opioid vs Regional Analgesia and Propofol: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery. Trial comparisons, record NCT00418457-1ec6fdd3. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00418457-1ec6fdd3
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.104 | 0.0873 | 0.124 | wilson | |
| Risk in group 2 | 0.0978 | 0.0812 | 0.117 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00643 | -0.0194 | 0.0323 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.07 | 0.826 | 1.38 | log | |
| Odds ratio, group 1 over group 2 | 1.07 | 0.808 | 1.43 | log | |
| Number needed to treat, for one more participant with the outcome on General Anesthesia and Opioid than on Regional Analgesia and Propofol | 156 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | General Anesthesia and Opioid | General anesthesia followed by opioid administration~General anesthesia and opioids: General anesthesia, usually with sevoflurane, and opioid analgesia | 111 | 1,065 | OG000 |
| Group 2 | Regional Analgesia and Propofol | Regional anesthesia and analgesia (either epidural or paravertebral) combined with propofol~Regional analgesia and propofol: Regional anesthesia and analgesia (either epidural or paravertebral), combined with deep sedation or general anesthesia | 102 | 1,043 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- PRIMARY
- Title
- Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery
- Description
- time to breast cancer recurrence from the end of surgery.
- Time frame
- up to 10 years
- Population
Source ClinicalTrials.gov
Trial
- Title
- Regional Anesthesia and Breast Cancer Recurrence
- NCT number
- NCT00418457
- Phases
- PHASE3
- Conditions
- Breast Neoplasms
- Interventions
- General anesthesia and opioids, Regional analgesia and propofol
- Lead sponsor
- The Cleveland Clinic
- Results first posted
- 2020-06-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00418457?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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