Comparison · NCT00425555-deaths
Bexarotene Exposed vs Bexarotene Naive: deaths from any cause
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Bexarotene Exposed vs Bexarotene Naive: deaths from any cause. Trial comparisons, record NCT00425555-deaths. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00425555-deaths
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.038 | 0.013 | 0.106 | wilson | |
| Risk in group 2 | 0.05 | 0.0171 | 0.137 | wilson | |
| Risk difference, group 1 minus group 2 | -0.012 | -0.103 | 0.0633 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 0.759 | 0.159 | 3.63 | log | |
| Odds ratio, group 1 over group 2 | 0.75 | 0.146 | 3.85 | log | |
| Number needed to treat, for one fewer death from any cause on Bexarotene Exposed than on Bexarotene Naive | 83.2 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Bexarotene Exposed | Participants received Panobinostat 20 mg/day capsule orally, OD on 3 days per week. (Monday, Wednesday and Friday or alternative Day 1, 3 and 5). Participants continued treatment until disease progression or unacceptable toxicity occurred. | 3 | 79 | EG000 |
| Group 2 | Bexarotene Naive | Participants received Panobinostat 20 mg/day capsule orally, OD on 3 days per week. (Monday, Wednesday and Friday or alternative Day 1, 3 and 5). Participants continued treatment until disease progression or unacceptable toxicity occurred. | 3 | 60 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, all-cause mortality
- Time frame
- From Start of the Study up to 7 years approximately
Source ClinicalTrials.gov
Trial
- Title
- Study of Oral LBH589 in Adult Patients With Refractory Cutaneous T-Cell Lymphoma
- NCT number
- NCT00425555
- Phases
- PHASE2
- Conditions
- Cutaneous T-Cell Lymphoma
- Interventions
- Panobinostat
- Lead sponsor
- Novartis Pharmaceuticals
- Results first posted
- 2021-08-16
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00425555?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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