Comparison · NCT00453986-2ebbb3e8
Nimenrix Group vs Mencevax ACWY Group: Number of Subjects Reporting Rash, in Subjects Receiving the Nimenrix (From the 3 Manufactured Lots Pooled) or the Mencevax ACWY Vaccines.
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Nimenrix Group vs Mencevax ACWY Group: Number of Subjects Reporting Rash, in Subjects Receiving the Nimenrix (From the 3 Manufactured Lots Pooled) or the Mencevax ACWY Vaccines. Trial comparisons, record NCT00453986-2ebbb3e8. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00453986-2ebbb3e8
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0107 | 0.00582 | 0.0196 | wilson | |
| Risk in group 2 | 0.00962 | 0.00328 | 0.0279 | wilson | |
| Risk difference, group 1 minus group 2 | 0.00108 | -0.0178 | 0.012 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.11 | 0.308 | 4.02 | log | |
| Odds ratio, group 1 over group 2 | 1.11 | 0.304 | 4.07 | log | |
| Number needed to treat, for one more participant with the outcome on Nimenrix Group than on Mencevax ACWY Group | 926 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Nimenrix Group | subjects received Nimenrix™ (Lots A without co-administration of FluarixTM vaccine, B and C) at Month 0. Nimenrix™ vaccine was administered by intramuscular injection in the deltoid region of the non-dominant arm. | 10 | 935 | OG000 |
| Group 2 | Mencevax ACWY Group | subjects received 1 dose of Mencevax™ ACWY vaccine at Month 0. Mencevax™ ACWY vaccine was administered by subcutaneous injection in the non-dominant upper arm. | 3 | 312 | OG001 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Subjects Reporting Rash, in Subjects Receiving the Nimenrix (From the 3 Manufactured Lots Pooled) or the Mencevax ACWY Vaccines.
- Description
Rash assessed were hives, idiopathic thrombocytopenic purpura and petechiae and were collected for all subjects of both cohorts receiving the Nimenrix vaccine (lot A without co-administration of Fluarix vaccine, lot B and lot C) or the Mencevax ACWY vaccine.
- Time frame
- From Dose 1 (at Month 0) up to study end (at Month 6)
- Population
- The Total Vaccinated Cohort included all vaccinated subjects for whom data were available.
Source ClinicalTrials.gov
Trial
- Title
- Lot Consistency, Immuno, Safety of Meningococcal Vaccine GSK134612 Given With Fluarix™ to 18-55 Year-Old Adults
- NCT number
- NCT00453986
- Phases
- PHASE3
- Conditions
- Infections, Meningococcal
- Interventions
- Meningococcal vaccine GSK134612, Mencevax™ACWY, Fluarix™
- Lead sponsor
- GlaxoSmithKline
- Results first posted
- 2012-05-22
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00453986?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT00453986-2ebbb3e8