E-ZES vs C-SES: To Compare Overall Definite or Probable Stent Thrombosis Rate of the Endeavor® Zotarolimus Eluting Coronary Stent System Versus the Cypher® Sirolimus-eluting Coronary Stent in a Patient Population Requiring Stent Implantation
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
Measures 6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note | Source |
|---|---|---|---|---|---|---|
| Risk in group 1 | 0.014 | 0.0109 | 0.0179 | wilson | ClinicalTrials.gov | |
| Risk in group 2 | 0.0172 | 0.0138 | 0.0215 | wilson | ClinicalTrials.gov | |
| Risk difference, group 1 minus group 2 | -0.00323 | -0.00854 | 0.00201 | newcombe hybrid score | ClinicalTrials.gov | |
| Risk ratio, group 1 over group 2 | 0.812 | 0.581 | 1.14 | log | ClinicalTrials.gov | |
| Odds ratio, group 1 over group 2 | 0.81 | 0.576 | 1.14 | log | ClinicalTrials.gov | |
| Number needed to treat, for one fewer participant with the outcome on E-ZES than on C-SES | 309 | from the risk difference interval | the interval includes no difference | ClinicalTrials.gov |
Groups 2
Neither group, or both, names a comparator, so the groups keep ClinicalTrials.gov's order.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code | Source |
|---|---|---|---|---|---|---|
| Group 1 | E-ZES | Medtronic Endeavor® Zotarolimus Eluting Coronary Stent System~Stent : Stent implantation | 61 | 4,357 | OG000 | ClinicalTrials.gov |
| Group 2 | C-SES | Cordis Cypher® Sirolimus-eluting Coronary Stent~Stent : Stent implantation | 75 | 4,352 | OG001 | ClinicalTrials.gov |
Outcome 5
| Field | Value | Source |
|---|---|---|
| Type | PRIMARY | ClinicalTrials.gov |
| Title | To Compare Overall Definite or Probable Stent Thrombosis Rate of the Endeavor® Zotarolimus Eluting Coronary Stent System Versus the Cypher® Sirolimus-eluting Coronary Stent in a Patient Population Requiring Stent Implantation | ClinicalTrials.gov |
| Description | Definite or probable stent thrombosis rate. | ClinicalTrials.gov |
| Time frame | 3 years | ClinicalTrials.gov |
| Population | ClinicalTrials.gov |
Trial 8
| Field | Value | Source |
|---|---|---|
| Title | Randomized Study Comparing Endeavor With Cypher Stents (PROTECT) | ClinicalTrials.gov |
| NCT number | NCT00476957 | ClinicalTrials.gov |
| Phases | PHASE4 | ClinicalTrials.gov |
| Conditions | Ischemic Heart Disease | ClinicalTrials.gov |
| Interventions | Stent, Stent | ClinicalTrials.gov |
| Lead sponsor | Medtronic Vascular | ClinicalTrials.gov |
| Results first posted | 2014-03-17 | ClinicalTrials.gov |
| Results on ClinicalTrials.gov | https://clinicaltrials.gov/study/NCT00476957?tab=results | ClinicalTrials.gov |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trial-comparisons-2026-03-23-0.1.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57 | ClinicalTrials.gov |
| AACT copy | 2026-03-23 | ClinicalTrials.gov |
| Tables read | outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet | ClinicalTrials.gov |
Release trial-comparisons-2026-03-23-0.1.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.