Comparison · NCT00483652-sae
Fampridine-SR 10 mg b.i.d. Treatment vs Placebo Treatment: serious adverse events
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
Cite this record
ConductScience Library. Fampridine-SR 10 mg b.i.d. Treatment vs Placebo Treatment: serious adverse events. Trial comparisons, record NCT00483652-sae. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00483652-sae
On this page
Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.0417 | 0.0179 | 0.0938 | wilson | |
| Risk in group 2 | 0.0252 | 0.00861 | 0.0715 | wilson | |
| Risk difference, group 1 minus group 2 | 0.0165 | -0.0356 | 0.0712 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1.65 | 0.404 | 6.76 | log | |
| Odds ratio, group 1 over group 2 | 1.68 | 0.393 | 7.2 | log | |
| Number needed to harm, for one more participant with a serious adverse event on Fampridine-SR 10 mg b.i.d. Treatment than on Placebo Treatment | 60.8 | from the risk difference interval | the interval includes no difference |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Fampridine-SR 10 mg b.i.d. Treatment | Fampridine-SR 10 mg b.i.d. dosing for 9 weeks | 5 | 120 | EG000 |
| Group 2 | Placebo Treatment | Placebo b.i.d. dosing for 9 weeks | 3 | 119 | EG001 |
Source ClinicalTrials.gov
Harm
- What it counts
- Total, serious adverse events
- Time frame
- 14 Weeks
Source ClinicalTrials.gov
Trial
- Title
- Study of Fampridine-SR Tablets in Multiple Sclerosis Patients
- NCT number
- NCT00483652
- Phases
- PHASE3
- Conditions
- Multiple Sclerosis
- Interventions
- Fampridine-SR, Placebo
- Lead sponsor
- Acorda Therapeutics
- Results first posted
- 2011-04-14
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00483652?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
For software
Read this comparison from software.
The record is JSON. No key.
GET https://conductscience.org/api/comparisons/v1/NCT00483652-sae