Comparison · NCT00486863-24ef5cea
Praziquantel at 12-16 Weeks Gestation vs Placebo Control at 12-16 Weeks Gestation: Number of Participants Whose Infant Was Born With Congenital Anomalies
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
2 sourcestrial-comparisons-2026-03-23-0.1.0
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ConductScience Library. Praziquantel at 12-16 Weeks Gestation vs Placebo Control at 12-16 Weeks Gestation: Number of Participants Whose Infant Was Born With Congenital Anomalies. Trial comparisons, record NCT00486863-24ef5cea. Release trial-comparisons-2026-03-23-0.1.0, 23 Mar 2026. https://conductscience.org/library/comparisons/NCT00486863-24ef5cea
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Measures6
Calculated by ConductScience from the counts the trial posted to ClinicalTrials.gov.
| Measure | Value | 95% interval, lower | 95% interval, upper | Method | Note |
|---|---|---|---|---|---|
| Risk in group 1 | 0.00552 | 0.000976 | 0.0306 | wilson | |
| Risk in group 2 | 0.00552 | 0.000976 | 0.0306 | wilson | |
| Risk difference, group 1 minus group 2 | 0 | -0.0255 | 0.0255 | newcombe hybrid score | |
| Risk ratio, group 1 over group 2 | 1 | 0.063 | 15.9 | log | |
| Odds ratio, group 1 over group 2 | 1 | 0.0621 | 16.1 | log | |
| Number needed to treat | from the risk difference interval | the two groups' risks are equal |
Source ClinicalTrials.gov
Groups2
Group 2 names the comparator: placebo.
| Group | Title | Description | With the outcome | Analysed | ClinicalTrials.gov code |
|---|---|---|---|---|---|
| Group 1 | Praziquantel at 12-16 Weeks Gestation | Praziquantel was administered orally as 60 mg/kg given in a split dose (30/mg/kg each) separated by 3 hours. | 1 | 181 | OG001 |
| Group 2 | Placebo Control at 12-16 Weeks Gestation | Placebo was made with the same color-coded gelatin capsules with the inert compound dextrose. | 1 | 181 | OG000 |
Source ClinicalTrials.gov
Outcome
- Type
- SECONDARY
- Title
- Number of Participants Whose Infant Was Born With Congenital Anomalies
- Description
The newborn was examined by the midwife at delivery and within 2-6 days of delivery to assess the presence of congenital anomalies and well-being. The newborn was also examined by study pediatrician at 28 days of life.
- Time frame
- At delivery, within 2-6 days of delivery, and at 28 days
- Population
- All newborns are included in the analysis.
Source ClinicalTrials.gov
Trial
- Title
- S. Japonicum and Pregnancy Outcomes
- NCT number
- NCT00486863
- Phases
- PHASE2
- Conditions
- Schistosomiasis
- Interventions
- Praziquantel, Placebo
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- Results first posted
- 2014-02-07
- Results on ClinicalTrials.gov
- https://clinicaltrials.gov/study/NCT00486863?tab=results
Source ClinicalTrials.gov
Source
- Release
- trial-comparisons-2026-03-23-0.1.0
- Release manifest SHA-256
- f66225897fbf258b57ea10bdacfd0347d3cdfda93f7f5685234b7e06ea36fa57
- AACT copy
- 2026-03-23
- Tables read
- outcome_counts.parquet, outcome_measurements.parquet, outcomes.parquet, reported_event_totals.parquet, reported_events.parquet, result_groups.parquet, studies.parquet, ctgov_trial.parquet
Source ClinicalTrials.gov
Sources 2
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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